Disperse and acid azo dyes having one or two cinnamoyl substituents on a benzothiazole or benzoisothiazole diazonium moiety and having an aniline, tetrahydroquinoline or benzomorpholine type coupler

ABSTRACT

This invention relates to azo dyes which may be unsubstituted or substituted with a variety of groups known to the dye art, and containing diazonium moieties from 2-aminobenzothiazole or 2-aminobenzisothiazole type compounds, and certain coupler moieties from aniline, tetrahydroquinoline, or benzomorpholine compounds, wherein the diazonium moieties have one or two cinnamoyl substituents, and wherein one or more water-solubilizing groups such as a sulfonic acid group or its metal or amine salt may be present as a substituent in the dye molecule for acid dyeing. These dyes are particularly useful in dyeing one or more of polyamide cellulose acetate polyester, wool and other fibers.

This invention relates to azo dyes containing diazonium moieties from 2-aminobenzothiazole or 3-aminobenzisothiazole type compounds, and certain coupler moieties from aniline, tetrahydroquinoline, and benzomorpholine type compounds, wherein the diazonium moieties have one or two cinnamoyl groups, and wherein a wide variety of groups, e.g., one or more water-solubilizing substituents such as sulfonic acid groups or their metal or amine salts may be present in the dye molecule. These dyes are useful for dyeing materials selected from polyamide, cellulose ester, polyester, wool and other natural and synthetic fibers and generally exhibit improvements in dyeability and fastness properties.

The present dyes have the general structure: ##STR1## wherein C¹ is an aniline, tetrahydroquinoline, or benzomorpholine type coupler which may be substituted; R is a divalent radical of benzothiazole or 2,1-benzisothiazole in accordance with one of the formulae below, which radical is unsubstituted or substituted in any positions not occupied by a cinnamoyl group, with 1-3 substituents preferably each of which is a substituent as defined for R¹ ; R₅ is H or alkyl; each R₁ is preferably alkyl, alkenyl of 2-6 carbons, aryl, cyclohexyl, alkoxy, halogen, hydroxy, alkylsulfonyl, cyano, carbamoyl, alkanoyl, alkanoyloxy, aroyl, alkoxycarbonyl, sulfamoyl, alkylsulfamoyl, dialkylsulfamoyl, alkanoylamino, SO₃ C₆ H₅, amino alkylthio, thiocyano, arylsulfonyl, formyl, alkylcarbamoyl, dialkylcarbamoyl, NO₂, --SO₃ M, --OSO₃ M, --COOH, aryloxy, arylthio, alkylsulfonylamino, aroylamino, arylsulfonylamino, or cyclohexylthio, wherein the alkyl, alkenyl aryl, and cyclohexyl moieties of the above R₁ groups, e.g., the alkyl portions of the alkanoyl groups, are unsubstituted or substituted with 1-3 substituents different from the said moieties and independently selected from alkanoyloxy, alkyl, alkenyl, succinimido (C₄ H₄ O₂ N), --NO₂, alkanoylamino, alkylsulfonylamino, 1-(2-pyrrolidono) (C₄ H₆ ON), halogen, cyano, alkoxy, aryl, cyclohexyl, hydroxy, --SO₃ M, --OSO₃ M, aryloxy, furyl (C₄ H₃ O), aroyloxy, alkoxycarbonyl, --SO₂ N-- (alkyl)₂, --NHCOO--alkyl, --NHCONH--alkyl, glutarimido (C₅ H₆ O₂ N), phthalimido (C₈ H₄ O₂ N), CONH₂, CONH-alkyl, CON(alkyl)₂, alkoxyalkoxy, alkylthio, arylthio, alkylsulfonyl, and arylsulfonyl, wherein M is selected from H⁺, NH₄ ⁺, Na⁺, K⁺, and the colorless cations of salts of primary, secondary, and tertiary aliphatic and arylamines, such as triethylamine, tri(2-hydroxyethyl)amine, di(2-hydroxyethyl)amine, N,N-dimethylaniline, and especially trimethylamine.

More particularly the R radical in the above dyes is selected from ##STR2## wherein each ring A and B carries 1 or 2 cinnamoyl groups defined above and is unsubstituted or substituted with 1-3 independently selected R₁ substituents.

The couplers C¹ preferably have the formulae: ##STR3## wherein R₁ is defined above; R₂ and R₇ are each selected independently from hydrogen, alkyl, alkenyl of 2-6 carbons, aryl, and cyclohexyl, all of which groups including alkylene moieties are unsubstituted or substituted as defined above for the substituted R₁ groups; and R₃, R₄ and R₈ are each selected from hydrogen and alkyl.

The various alkyl and alkylene moieties such as contained, for example, in alkoxy, alkanoyl, and alkoxyalkoxy groups within the above definitions, preferably contain 1-6 carbons, and they and the alkenyl groups may be straight or branched chain, and the above aryl groups preferably contain from 6-10 ring carbons

The following are typical specific R₁ groups: CH₃, Cl, SO₂ C₂ H₅, CN, CONH₂, COC₂ H₅, COC₆ H₅, COOC₂ H₅, SO₂ NH₂, SO₂ NHCH₃, SO₂ N(C₂ H₅)₂, NHCOC₂ H₅, SO₃ C₆ H₅, SCH₃, SCN, SO₂ C₆ H₅, CHO, CONHC₂ H₅, CON(C₂ H₅)₂, OH, NO₂, C₆ H₅, C₆ H₁₁, SO₃ K, CF₃, CH₂ OOCC₂ H₅, Br, SO₂ CH₂ CH₂ OC₂ H₅, I, CONHCH₂ CN, COCH₂ CH₂ OH, COC₆ H₃ -o-CH₃ -p-OCH₃, COOC₂ H₄ -CH═CH₂, SO₂ NHCH₂ CH₂ CN, SO₂ NHCH₂ - succinimido, SO₂ NHC₂ H₄ -C₆ H₅, NHCOCH₂ CH₂ Cl, SO₃ C₆ H₄ -p-NO₂, SCH.sub. 2 CH₂ OH, SC₂ H₄ -C₆ H₁₁, SO₂ C₆ H₄ -p-NHCOCH₃, C₆ H₄ -p-NHSO₂ CH₃, CONHC₂ H₄ NHSO₂ CH₃, CONHCH₂ CH₂ OH, CH₂ CH₂ NO₂, C₆ H₄ -p-(2-pyrrolidono), C₆ H₁₀ -4-CN, OSO₃ K, CH₂ SO₃ Na, OC₆ H₅, SO₂ C₂ H₄ OSO₃ K, C₂ H₄ -furyl, C₂ H₄ OOCC₆ H₅, COCH₂ CH₂ COOCH₃, COC₆ H₄ -p-SO₂ NHC₆ H₅, COOCH₂ CH₂ -SO₂ NHCH₃, SO₂ NHCH₂ SO₂ N(C₂ H₅)₂, SO₂ NHCH₂ NHCOOCH₃, SO₂ NHC₂ H₄ NHCONHCH₃, NHCOCH₂ CH₂ -glutarimido, SO₃ C₆ H₄ -p-phthalimido, SCH₂ CONH₂, C₆ H₄ -p-SO₂ CH₃, SO₂ C₆ H₄ -p- CONHCH₂ SO₃ Na, CH₂ SO₂ C₆ H₅, CONHCH₂ CH₂ CON(CH₃)₂, CONHCH₂ CH₂ OCH₂ CH₂ OCH₂ CH₃, CH₂ CH₂ SO₃ H, C₆ H₄ -p-SC₂ H₅, C₆ H₁₀ -4-SC₆ H₄ (4-OSO₃ H), CH₂ CH═CH₂, COOH, OC₆ H₅, OCH₃, SC₆ H₅, NHSO₂ CH₃, NHCOC₆ H₅, NH₂, NHSO₂ C₆ H₅, SC₆ H₁₁, and -OOCCH₃.

Typical for R₃, R₄, R₅ and R₈ are: H, CH₃, C₂ H₅, C₄ H₉ -n, and CH₂ (CH₃)₂.

The following are typical specific R₂ and R₇ substituents: H, CH₃, C₂ H₅, C₄ H₉ -n, CH₂ CH═CH₂, C₆ H₅, C₆ H₁₁, CH₂ OOCC₂ H₅, CH₂ CH₂ OC₂ H₅, CH₂ CN, CH₂ CH₂ OH, C₆ H₃ -o-CH₃ -p-OCH₃, C₂ H₄ -CH═CH₂, CH₂ -succinimido, CH₂ CH₂ -C₆ H₅, CH₂ CH₂ Cl, C₆ H₄ -p-NO₂, CH₂ CH₂ C₆ H₁₁, C₆ H₄ -p-NHSO₂ CH₃, C₂ H₄ NHSO₂ CH₃, CH₂ CH₂ NO₂, C₆ H₄ -p-(2-pyrrolidono), C₆ H₁₀ -4-CN, CH₂ SO₃ Na, CH₂ CH₂ OSO₃ K, CH₂ CH₂ -furyl, CH₂ CH₂ OOCC₆ H₅, CH₂ CH₂ COOCH₃, C₆ H₅ -p-SO₂ NHC₆ H₅, CH₂ CH₂ SO₂ NHCH₃, CH₂ SO₂ N(C₂ H₅)₂, CH₂ NHCOOCH₃, CH₂ CH₂ NHCONHCH₃, CH₂ CH₂ -glutarimido, C₆ H₄ -p-phthalimido, CH₂ CONH₂, C₆ H₄ -p-SO₂ CH₃, C₆ H₄ -p-CONHCH₂ SO₃ Na, CH₂ SO₂ C₆ H₅, CH₂ CH₂ CON(CH₃)₂, CH₂ CH₂ OCH₂ CH₂ OC₂ H₅, CH₂ CH₂ SO₃ H, C₆ H₄ -p-SC₂ H₅, and C₆ H₁₀ -4-SC₆ H₄ (p-OSO₃ H).

Preferred for the A and B rings are R₁ being H, methoxycarbonyl, β-hydroxyethylcarbamoyl, halogen CF₃, CN, alkanoyl, NO₂, alkylsulphonyl β-potassiosulfatoethylcarbamoyl, methylcarbamoyl, carbamoyl, ethoxycarbonyl, or methyl; for R₁ on the cinnamoyl rings are H, alkyl, aralkyl, aralkyl substituted with --SO₃ M or --SO₄, cyclohexylalkyl, cyclohexylalkyl substituted with --SO₃ M or --SO₄ M, alkoxy, or alkanoylamino; for R₂ are H, alkyl, aralkyl, alkyl or aralkyl substituted with --SO₃ M or --SO₄ M, cyclohexylalkyl, cyclohexylalkyl substituted with --SO₃ M or --SO₄ M; for R₇ are H, alkyl, aralkyl, aralkyl substituted with --SO₃ M or --SO₄ M, cyclohexylalkyl, cyclohexylalkyl substituted with --SO₃ M or --SO₄ M, sodio- or potassiosulfatoalkyl, sodio- or potassiosulfonicalkyl, or alkanoyloxyalkyl; for R₁ on the couplers are H, aralkyl, aralkyl substituted with --SO₃ M or --SO₄ M, alkanoylamino, aroylamino, cyclohexylalkyl, cyclohexylalkyl substituted with --SO₃ M or --SO₄ M, --SO₃ Na, --SO₃ K, halogen, --SO₄ Na, --SO₄ K, alkyl, alkoxy, --COOH, or --OH; for R₃, R₄ and R₈ are H and alkyl; and for R₅ is hydrogen.

The dyes of this invention impart red to blue shades on natural and synthetic fibers and exhibit improvements over such dyes as disclosed in U.S. Pat. No. 2,805,218 and British Pat. No. 1,021,399 in one or more properties such as fastness to light, ozone, chlorine, oxides of nitrogen, washing, sublimation, heat disintegration, perspiration, and crocking, leveling, transfer, exhaustion, build, pH stability, and resistance to blooming.

The intermediate compounds used in this invention are prepared according to procedures well known to the art. The present dyes are readily prepared, for example, by reacting the acetyl group of the intermediate azo compound, which itself is a dye, with benzaldehyde or a substituted benzaldehyde in acetic acid with concentrated sulphuric acid as catalyst. The acetyl dye is thus converted to a cinnamoyl substituted dye in high yield. The water-solubilizing group may be the substituent on the benzaldehyde or it may be introduced into the cinnamoyl dye at a later stage by known methods. For example, a hydroxy group in either the diazonium component or the coupling component could be reacted with sulphuric acid and then with MOH to give the --OSO₃ M group. Alternatively a chloroalkyl group in the dye could be reacted with K₂ SO₃ to give the --CH₂ SO₃ K group. Also, sulphonation of an aromatic ring or other reactive group in the dye with a sulphonating agent such as H₂ SO₄ or Cl--SO₃ H would give the solubilizing group. Such groups could also be present in the coupling component prior to diazotisation and coupling.

The following Preparations, Example and tables will illustrate the making and use of intermediates for the synthesis of dyes of the present invention.

PREPARATION A α-(N-Ethylanilino)-Toluenesulfonic Acid

To 30.0 g. of 100% sulfuric acid is added N-benzyl-N-ethylaniline (30.0 g.) dropwise below about 50° C. To this solution is added, at 50°-60° C., 60% oleum (30.0 g.) with good stirring. The mixture is stirred and heated at about 60° C. for three hours and then drowned into 200 ml. of water. The free sulfonic acid (Coupler 1) which is mostly the meta isomer with a small amount of para, precipitates on standing and is collected by filtration, washed with water, and dried. N-Benzylanilines containing groups such as alkyl, alkoxy, and halogen in the ortho, meta, or para positions of the benzyl group may also be sulfonated by this procedure. The exact location of the sulfonic acid group in these cases is often not known and mixtures usually are produced.

Aromatic amines which contain N-aralkyl groups and which are sulfonated by the above procedure to give Couplers 2 to 11 are listed below.

    ______________________________________                                         COUPLER NO.   Sulfonation product of:                                          ______________________________________                                         2             N--Benzyl-N--ethyl-m-toluidine;                                  3             N--Benzyl-2,7-dimethyl-1,2,3,4-                                                tetrahydroquinoline;                                             4             N--Benzyl-2,3-dihydro-3,6-dimethyl-                                            1,4-benzoxazine;                                                 5             N--Methyl-N--(2-phenylethyl)aniline;                             6             N--Ethyl-N--(4-phenylbutyl)-3-                                                 chloroaniline;                                                   7             N,N--Dibenzylaniline;                                            8             N--Benzyl-2,5-dimethylaniline;                                   9             N--Benzyl-2-methoxy-5-methylaniline;                             10            N--Benzyl-2-methoxy-5-chloroaniline;                                           and                                                              11            N--Benzyl-N--cyclohexylaniline.                                  ______________________________________                                    

PREPARATION B Diazotization and Coupling of 2-Amino-6-Acetylbenzothiazole

To 150 g. of 60% acetic acid containing 10 g. of concentrated H₂ SO₄ is added 0.055 m. of 2-amino-6-acetylbenzothiazole at room temperature. The solution is cooled to -5° C., and a solution of 3.6 g. NaNO₂ in 20 ml. of concentrated H₂ SO₄ is added below 0° C. The reaction mixture is stirred at -5° to 0° C. for 1.5 hours. Each of the Couplers 1 to 11.0 (0.005 m.) listed is added to water, or a 0.005 mole aliquot of the coupler in dilute sulfuric acid is added to water, and cooled in an ice bath.

To each chilled coupler is added a 0.005 mole aliquot of the diazonium solution. The coupling mixture is treated with enough potassium acetate to neutralize the mineral acid. Water is added to the coupling mixture to a total volume of about 200 ml. and the dyes collected by filtration, washed with 10% KCl solution, and dried in air. The dyes usually are admixed with about an equal weight of K₂ SO₄ and are used for dyeing without further purification to produce red shades on polyamides. These dyes are intermediates for the preparation of dyes of the present invention.

PREPARATION C Diazotization and Coupling of 3-Amino-5-acetyl-2,1-benzisothiazole

To 25 ml. of concentrated H₂ SO₄ is added 3.6 g. of NaNO₂ portionwise below 80° C. The solution is cooled and 50 ml. of 1:5 acid (1 part propionic, 5 parts acetic acid) is added below 20° C. The mixture is further cooled and 3-amino-5-acetyl-2,1-benzisothiazole 0.055 m. is added, followed by 50 ml. of 1:5 acid, all at 0°-5° C. The diazonium, after stirring at 0°-5° C. for 1 hr., is coupled to each of the Couplers 1-11 in a similar manner as above to produce violet to reddish blue dyes for polyamides.

PREPARATION D Sulfonation of Dye Containing an N-(Aralkylamino) Group

The dye from 2-amino-5-acetyl-2,1-benzisothiazole and N-benzyl-N-ethylaniline (2.0 g.) is added portionwise to 15 ml. of concentrated H₂ SO₄ over 20 min., allowing the temperature to rise to 30° C. The reaction mixture is then heated at 70° C., and when the reaction is completed as evidenced by thin-layer chromatography, the reaction mixture is drowned on ice-water mixture, and 50% NaOH is added until the pH is about 7. The dye is collected by filtration, washed with water, and dried in air. The dye has the structure ##STR4##

EXAMPLE Final Dye Preparation ##STR5##

A mixture of compound (I) (2 g.), benzaldehyde (1.5 g.), acetic acid (25 ml.) and concentrated sulphuric acid (5 ml.) was stirred at 100° C. for 1.5 hours. The reaction mixture was poured into cold water and the produce dye (II) filtered off, washed with water and dried. Compound (I) had previously been prepared by diazotising the known 2-amino-6-acetylbenzothiazole and coupling with N,N-diethyl-m-toluidine by known procedures. The dye (II) when applied to nylon, polyester and other synthetic fibres by known techniques gives bright, bluish red shades with good dyeing and fastness properties.

By using the methods described hereinabove, the following dyes are obtained.

    TABLE 1       ##STR6##        Cinnamoyl       Group   Substituents Position R.sub.1 on D R.sub.5 on      A R.sub.1 on C R.sub.2 R.sub.7        6 H H H H H H 6 4-NO.sub.2 H 4-COCH.sub.3 2-CH.sub.3 C.sub.2 H.sub.5      Ph 6 4-CN H 4-NO.sub.2 5-COCH.sub.3 C.sub.2 H.sub.5 C.sub.6 H.sub.11 6      5-COCH.sub.3 H 4-Cl 5-OCH.sub.3 CH.sub.2C.sub.6 H.sub.4-p-SO.sub.4 K      CH.sub.2CHCH.sub.2 7 4-COPh CH.sub.3 4-CN 5-SO.sub.3 Na H CH.sub.2      OOCC.sub.2 H.sub.5 5 2,4-di-COOH CH.sub.3 4-NHSO.sub.2       CH.sub.3 5-OCH.sub.2 CH.sub.2 SO.sub.4 K CH.sub.2C.sub.6       H.sub.104-SO.sub.3 K C.sub.6 H.sub.4-p-OOCCH.sub.3 6 4-OOCCH.sub.3      CH.sub.3 7-CH.sub.3 5-OCH.sub.2 CH.sub.2 SO.sub.4 NH(Et).sub.3 H C.sub.6      H.sub.104-CH.sub.3   5,6 4-NHCOCH.sub.3 CH.sub.3 7-OCH.sub.3 2-CH.sub.3      CH.sub.2C.sub.6 H.sub.4-p-SO.sub.4 N H(Et).sub.3 CH.sub.2 CH.sub.2      (C.sub.4 H.sub.4 O.sub.2 N) 6 4-NHCOPh CH.sub.3 4-Ph 2-Ph CH.sub.3      CH.sub.2 CH.sub.2 NO.sub.2 4 4-C.sub.2 H.sub.5 CH.sub.3 H 2-NO.sub.2      CH.sub.3 C.sub.6 H.sub.5-p-NO.sub.2 6 4-Ph H H 2-OCH.sub.3 CH.sub.3      CH.sub.2 NHOCCH.sub.3   5,6 2,5-di-Cl H 4-SO.sub.3 Na 5-NHCOCH.sub.3      C.sub.2 H.sub.5 CH.sub.2 NHSO.sub.2 CH.sub.3 6 2-Cl4-SO.sub. 2 CH.sub.3      H 4-SO.sub.3 Na 3-NHSO.sub.2 CH.sub.3 C.sub.2 H.sub.5 C.sub.6       H.sub.4-p-NHOCCH.sub.3 6 4-NHSO.sub.2 CH.sub.3 H 7-OCH.sub.2 CH.sub.2      SO.sub.4 K 3-COOCH.sub.3 C.sub.2 H.sub.5 C.sub.6 H.sub.4-p-NHSO.sub.2      CH.sub.3 6 4-COOCH.sub.3 H 7-OCH.sub.2 CH.sub.2 SO.sub.4 K 3-COOH      C.sub.2 H.sub.5 C.sub.6 H.sub.104-NHOOCH.sub.3 6 2-OCH.sub.3 C.sub.2      H.sub.5 4-NHCOPh 2-Cl CH.sub.2 CH.sub.2 Cl CH.sub.2 CH.sub.2 Cl 5      4-OC.sub.2 H.sub.5 C.sub.2 H.sub.5 4-NHCOPh 2,6-di-Br C.sub.6       H.sub.4-p-Br C.sub.6 H.sub.4-p-Br 6 4-SO.sub.3 Na C.sub.2 H.sub.5      7-NHCOCH.sub.3 2,6-di-Br C.sub.6 H.sub.4-p-CN C.sub.6 H.sub.4-p-CN 6      2-SO.sub.3 Na C.sub.2 H.sub.5 7-OOCC.sub.2       H.sub.5 2-OCH.sub.35-NHCOCH.sub.3 CH.sub.2 CH.sub.2 CN CH.sub.2      CH.sub.2 CN 7 2-OCH.sub.34-SO.sub.3 K H 4-COOH 2-CH.sub.2 OOCCH.sub.3      CH.sub.2 CH.sub.2 OC.sub.2 H.sub. 5 CH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 6      4-OCH.sub.2 CH.sub.2 OSO.sub.3 K H H 2-CH.sub.2 Cl CH.sub.2 CH.sub.2      OCH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 CH.sub.2 CH.sub.2 OCH.sub.2 CH.sub.2      OC.sub.2 H.sub.5 6 2-SO.sub.3 Na5-Cl H H 2-CN CH.sub.2       Ph CH.sub.2C.sub.6 H.sub.4-p-SO.sub.4 N H(Et).sub.3 6 4-Cl H 7-SO.sub.2      CH.sub.3 2-OOCCH.sub.3 CH.sub.2 C.sub.6 H.sub.11 CH.sub.2 C.sub.6      H.sub.104-SO.sub.3 Na 6 4-OH H 7-CF.sub.3 5-COOH H C.sub.6 H.sub.4-o-OH      6 4-CH.sub.2 OOCCH.sub.3 C.sub.3 H.sub.7n 7-COOCH.sub.3 5-OH C.sub.2      H.sub.5 CH.sub.2 CH.sub.2 OH   5,6 4-SO.sub.3 K C.sub.3 H.sub.7n 7-CHO      5-CH.sub.2 CHCH.sub.2 CH.sub.2 CH.sub.2SO.sub.3 K CH.sub.2       CH.sub.2SO.sub.3 K 6 4-OPh H 7-CONH.sub.2 2-CH.sub.3 H CH.sub.2C.sub.6      H.sub.4-p-OSO.sub.3 K 6 4-NO.sub.2 H 7-CONHCH.sub.3 5-COCH.sub.3 H      CH.sub.2 OPh 6 5-CN H 7-CH.sub. 2 Ph 5-OCH.sub.3 H CH.sub.2 SO.sub.2      NHPh 6 4-COCH.sub.3 H 7-CH.sub.2 SO.sub.3 K 5-SO.sub.3 Na CH.sub.2      SO.sub.2 NHCH.sub.3 CH.sub.2 SO.sub.2       NHCH.sub.3 6 5-CH.sub.3 H 7-CH.sub.2 OSO.sub.3 K 5-OCH.sub.2 CH.sub.2      SO.sub.4 K H CH.sub.2 C.sub.6 H.sub.4-p-SO.sub.2 NHCH.sub.3 6 5-C.sub.6      H.sub.4-p-SO.sub.3 K H 7-C.sub.6 H.sub.4-p-SO.sub.3 K 5-OCH.sub.2      CH.sub.2 SO.sub.3 K CH.sub.2 COOCH.sub.3 CH.sub.2       COOCH.sub.3 6 5-OCH.sub.3 H 7-CH.sub.2 CH.sub.2 OH 2-CH.sub.3 H      CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2 6 4,5-di-Br H 7-CH.sub.2       Cl 2-C.sub.6 H.sub.4-p-SO.sub.3 K C.sub.2 H.sub.5 C.sub.6       H.sub.4-p-NHCOCO.sub.3 6 5-COOH C.sub.4 H.sub.9n 7-C.sub.6 H.sub.4-p-Br      2-NO.sub.2 C.sub.2 H.sub.5 CH.sub.2 CH.sub.2       CONH.sub.2 6 H H H 2-OCH.sub.3 C.sub.2 H.sub.5 C.sub.6       H.sub.4- p-CONHCH.sub.3 6 4-NO.sub.2 H 4-COCH.sub.3 5-NHCOCH.sub.3      C.sub.2 H.sub.5 C.sub.6       H.sub.4-p-SCH.sub.3 6 4-CN H 4-NO.sub.2 3-NHSO.sub.2 CH.sub.3 CH.sub.2      CH.sub.2 SCH.sub.3 CH.sub.2 CH.sub.2 SCH.sub.3 6 5-COCH.sub.3 H 4-Cl      3-COOCH.sub.3 H CH.sub.2C.sub.6 H.sub.4-p-SCH.sub.3 6 4-COPh CH.sub.3      4-CN 3-COOH CH.sub.2 SO.sub.2 C.sub.2 H.sub.5 CH.sub.2 SO.sub.2 C.sub.2      H.sub.5 6 2,4-di-COOH CH.sub.3 4-NHSO.sub.2 CH.sub.3 2-Cl H CH.sub.2      SO.sub.2 Ph 6 4-OOCCH.sub.3 CH.sub.3 7-CH.sub.3 2,6-di-Br H CH.sub.2      CH.sub.2 OSO.sub.3 K 6 4-NHCOCH.sub.3 CH.sub.3 7-OCH.sub.3 2,6-di-Br H      C.sub.6 H.sub.4-p-OSO.sub.3       K 6 4-NHCOPh CH.sub.3 4-Ph 2-OCH.sub.35-NHCOCH.sub.3 H CH.sub.2      (C.sub.8 H.sub.4 O.sub.2 N) 5 4-CH.sub.2 CHCH.sub.2 H H 3-NHCOCH.sub.3      C.sub.2 H.sub.5 C.sub.2 H.sub.5   4,6 H CH.sub.3 H 3-OCPh C.sub.2      H.sub.5 C.sub.2 H.sub.5 6 4-CONH.sub.2 H H 5-CH.sub.2 CONHCH.sub. 3 H H      6 3-SO.sub.2 NH.sub.2 H 4-COCH.sub.3 5-CH.sub.2 CON(CH.sub.3).sub.2      C.sub.2 H.sub.5 Ph 6 4-SO.sub.2 NHCH.sub.3 H 4-NO.sub.2 5-CH.sub.2      CH.sub.2 OCH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 C.sub.2 H.sub.5 C.sub.6      H.sub.11 6 4-SO.sub.2 N(C.sub.2 H.sub.5).sub.2 H 4-Cl 5-CH.sub.2      SC.sub.2 H.sub.5 H CH.sub.2CHCH.sub.2 7 4-SO.sub.3 C.sub.6 H.sub.5      CH.sub.3 4-CN 2-CH.sub.2 SC.sub.6 H.sub.5 H CH.sub.2 OOCC.sub.2 H.sub.5      5 4-SCH.sub.3 CH.sub.3 4-NHSO.sub.2 CH.sub.3 5-CH.sub.2 SO.sub.2 C.sub.2      H.sub.5 H C.sub.6 H.sub.4-p-OOCCH.sub.3 6 2,4-di-SCN CH.sub.3 7-CH.sub.3      5-CH.sub.2 SO.sub.2 C.sub.6 H.sub.5 H C.sub.6 H.sub.104-CH.sub.3 6      4-SO.sub.2 C.sub.6 H.sub.5 CH.sub.3 7-OCH.sub.3 5-C.sub.6       H.sub.3-o,-p-di-CN H CH.sub.2 CH.sub.2 (C.sub.4 H.sub.4 O.sub.2 N) 6      2-CHO4-CN CH.sub.3 4-Ph 5-C.sub.6 H.sub.2-o,.sub.-- m,-p-tri-Cl CH.sub.3      CH.sub.2 CH.sub.2 NO.sub.2 4 4-CONHC.sub.2       H.sub.5 CH.sub.3 H 2,6-di-OSO.sub.3 N H(CH.sub.3).sub.3 CH.sub.3      C.sub.6 H.sub.4-p-NO.sub.2 6 4-CON(C.sub.2       H.sub.5).sub.2 H H 2,6-di-SO.sub.3 N H(CH.sub.3).sub.3 CH.sub.3      CH.sub.2 NHOCCH.sub.3 6 3-C.sub.6 H.sub.11 H 4-SO.sub.3       Na 2,6-di-OSO.sub.3 K C.sub.2 H.sub.5 CH.sub.2 NHSO.sub.2 CH.sub.3 6      3-SC.sub.6 H.sub.5 H 4-SO.sub.3 Na 2-SO.sub.3 N H(CH.sub.3).sub.3      C.sub.2 H.sub.5 C.sub.6 H.sub.4-p-NHOCCH.sub.3 6 4-NHSO.sub.2 C.sub.6      H.sub.5 H 7-OCH.sub.2 CH.sub.2 SO.sub.4 K 2-OSO.sub.3       N H(CH.sub.3).sub.3 C.sub.2 H.sub.5 C.sub.6 H.sub.4-p-NHSO.sub.2      CH.sub.3 6 4-SC.sub.6 H.sub.11 H 7-OCH.sub.2 CH.sub.2 SO.sub.4 K      5-SC.sub.6 H.sub.11 C.sub.2 H.sub.5 C.sub.6 H.sub.104-NHOCCH.sub.3 6      4-C.sub.6 H.sub.4p-CH.sub.3 C.sub.2 H.sub.5 4-NHCOPh 5-C.sub.6       H.sub.4-p-CH.sub. 3 CH.sub.2 CH.sub.2 Cl CH.sub.2 CH.sub.2 Cl 5      4-C.sub.6 H.sub.4p-CH.sub.2 CHCH.sub.2 C.sub.2       H.sub.5 4-NHCOPh 5-C.sub.6 H.sub.4-p-CH.sub.2 CHCH.sub.2 C.sub.6      H.sub.4-p-Br C.sub.6 H.sub.4-p-Br 6 4-OCH.sub.2 CH.sub.2 NO.sub.2      C.sub.2 H.sub.5 7-NHCOCH.sub.3 5-OCH.sub.2 CH.sub.2 NO.sub.2 C.sub.6      H.sub.4-p-CN C.sub.6 H.sub.4-p-CN 6 2-CH.sub.2 NHCOCH.sub.3 C.sub.2      H.sub.5 7-OOCC.sub.2 H.sub.5 2-CH.sub.2 NHCOCH.sub.3 CH.sub.2 CH.sub.2      CN CH.sub.2 CH.sub.2 CN 7 4-CH.sub.2 NHSO.sub.2 C.sub.2 H.sub.5 H 4-COOH      5-CH.sub.2 NHSO.sub.2 C.sub.2 H.sub.5 CH.sub.2 CH.sub.2 OC.sub.2 H.sub.5      CH.sub.2 CH.sub.2 OC.sub.2 H.sub.5   6,7 4-CH.sub.2 CH.sub.2 Cl H H      5-CH.sub.2 CH.sub.2 Cl CH.sub.2 CH.sub.2 OCH.sub.2 CH.sub.2 OC.sub.2      H.sub.5 CH.sub.2 CH.sub.2 OCH.sub.2 CH.sub.2 OC.sub.2       H.sub.5 6 2,6-di-CH.sub.2 CN H H 2,6-di-CH.sub.2 CN CH.sub.2 Ph      CH.sub.2 Ph 6 4-CH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 H 7-SO.sub.2 CH.sub.3      5-CH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 CH.sub.2 C.sub.6 H.sub.11 CH.sub.2      C.sub.6 H.sub.11 6 4-CH.sub.2 C.sub.6 H.sub.5 H 4-CH.sub.2 C.sub.6      H.sub.5 5-COOH H C.sub.6 H.sub.4-o-OH 6 4-CH.sub.2 C.sub.6 H.sub.11      C.sub.3 H.sub.7n 7-COOCH.sub.3 5-CH.sub.2 C.sub.6 H.sub.11 C.sub.2      H.sub.5 CH.sub.2 CH.sub.2 OH 6 4-CH.sub.2 CH(OH)CH.sub.2 OH C.sub.3      H.sub.7n 7-CHO 5-CH.sub.2 CH(OH)CH.sub.2 OH CH.sub.2 CH.sub.2SO.sub.3 K      CH.sub.2 CH.sub.2SO.sub.3 K 6 4-CH.sub.2 CH.sub.2SO.sub.3       K H 7-CONH.sub.2 5-CH.sub.2 CH.sub.2SO.sub.3 K H C.sub.6       H.sub.4-p-OSO.sub.3 K 6 4-CH.sub.2 OC.sub.6 H.sub.5 H 7-CONHCH.sub.3      5-CH.sub.2 OC.sub.6 H.sub.5 H CH.sub.2 OPh 6 4-CH.sub.2 OOCC.sub.6      H.sub.5 H 7-CH.sub.2 Ph 5-CH.sub.2 OOCC.sub.6 H.sub.5 H CH.sub.2 SO.sub.      2 NHPh 6 5-CH.sub.2 COOCH.sub.3 H 7-CH.sub.2 SO.sub.3 K 5-CH.sub.2      COOCH.sub.3 CH.sub.2 SO.sub.2 NHCH.sub.3 CH.sub.2 SO.sub.2 NHCH.sub.3 6      4-C.sub.6 H.sub.4-p-SO.sub.2 N(C.sub.2 H.sub.5).sub.2 H 7-CH.sub.2      OSO.sub.3 K 5-C.sub.6 H.sub.4-p-SO.sub.2 N(C.sub.2 H.sub.5).sub.2 H      C.sub.6 H.sub.4-p-SO.sub.2 NHCH.sub.3 6 4-CH.sub.2 CH.sub.2       NHCOOCH.sub.3 H 7-C.sub.6 H.sub.4-p-SO.sub.3 K 5-CH.sub.2 CH.sub.2      NHCOOCH.sub.3 CH.sub.2 COOCH.sub.3 CH.sub.2 COOCH.sub.3 6 4-CH.sub.2      NHCONHCH.sub.3 H 7-CH.sub.2 CH.sub.2 OH 5-CH.sub.2 NHCONHCH.sub.3 H      CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2 6 4-CH.sub.2 CONH.sub.2 H 7-CH.sub.2      Cl 5-CH.sub.2 CONH.sub.2 C.sub.2 H.sub.5 C.sub.6 H.sub.4-p-NHCOOCH.sub.3      6 5-CH.sub.2 CONHCH.sub.3 C.sub.4 H.sub.9n 7-C.sub.6 H.sub.4-p-Br      5-CONH.sub.2 C.sub.2 H.sub.5 CH.sub.2 CH.sub.2 CONH.sub.2 6 4-CH.sub.2      CON(CH.sub. 3).sub.2 H H 3-SO.sub.2 NH.sub.2 C.sub.2 H.sub.5 C.sub.6      H.sub.4-p-CONHCH.sub.3 6 4-CH.sub.2 CH.sub.2 OCH.sub.2 CH.sub.2 OC.sub.2      H.sub.5 H 4-COCH.sub.3 5-SO.sub.2 NHCH.sub.3 C.sub.2 H.sub.5 C.sub.6      H.sub.4-p-SCH.sub.3   6,7 4-CH.sub.2 SC.sub.2 H.sub.5 H 4-NO.sub.2      5-SO.sub.2 N(C.sub.2 H.sub.5).sub.2 CH.sub.2 CH.sub.2 SCH.sub.3 CH.sub.2      CH.sub.2 SCH.sub.3 6 5-CH.sub.2 SC.sub.6 H.sub.5 H 4-Cl 5-SO.sub.3      C.sub.6 H.sub.5 H CH.sub.2C.sub.6 H.sub.4-p-SCH.sub.3 6 4-CH.sub.2      SO.sub.2 C.sub.2 H.sub.5 CH.sub.3 4-CN 5-SCH.sub.3 CH.sub.2 SO.sub.2      C.sub.2 H.sub.5 CH.sub.2 SO.sub.2 C.sub.2 H.sub.5 6 2,4-di-CH.sub.2      SO.sub.2 C.sub.6 H.sub.5 CH.sub.3 4-NHSO.sub.2 CH.sub.3 2,5-di-SCN H      CH.sub.2 SO.sub.2 Ph 6 4-C.sub.6 H.sub.3-o,-p-di-CN CH.sub.3 7-CH.sub.3      5-SO.sub.2 C.sub.6 H.sub.5 H CH.sub.2 CH.sub.2 OSO.sub.3 K 6 4-C.sub.6      H.sub.2-o,.sub.--m,-p-tri-Cl CH.sub.3 7-OCH.sub.3 2-CHO6-CN H C.sub.6      H.sub.4-p-OSO.sub.3 K 6 2,6-di-OSO.sub.3 Na CH.sub.3 4-Ph 5-CONHC.sub.2      H.sub.5 H CH.sub.2(C.sub.8 H.sub.4 O.sub.2 N) 6 H H 7-CH.sub.2 (C.sub.4      H.sub.4 O.sub.2 N) 5-CON(C.sub.2 H.sub.5).sub.2 C.sub.2 H.sub.5 C.sub.2      H.sub.5 6 H H 7-CH.sub.2 (C.sub.4 H.sub.3 O) 3-C.sub.6 H.sub.11 C.sub.2      H.sub.5 C.sub.2 H.sub.5 6 5-CH.sub.2 (C.sub.8 H.sub.4 O.sub.2 N) H H      3-SC.sub.6 H.sub.5 C.sub.2 H.sub.5 C.sub.2 H.sub.5 6 5-CH.sub.2 (C.sub.4      H.sub.3 O) H H 6-NHSO.sub.2 C.sub.6 H.sub.5 C.sub.2 H.sub.5 C.sub.2      H.sub.5 5 2-SO.sub.3 Na H H 3NHCOCH.sub.3 C.sub.2 H.sub.5 C.sub.2      H.sub.5 5 H H H 3NHCOCH.sub.3 C.sub.2 H.sub.5 C.sub.2       H.sub.5

    TABLE 2       ##STR7##        Cinnamoyl Group         Position R.sub.1 on D R.sub.5 Substituents on      A R.sub.1 on C R.sub.3 R.sub.4 R.sub.8 R.sub.7        6 H H H H H H H H 6 4-NO.sub. 2 H 4-COCH.sub.3 7-CH.sub.3 CH.sub.3      CH.sub.3 CH.sub.3 Ph 6 4-CN H 4-NO.sub.2 5-COCH.sub.3 CH.sub.3 CH.sub.3      H C.sub.6 H.sub.11 6 5-COCH.sub.3 H 4-Cl 5-OCH.sub.3 CH.sub.3 CH.sub.3 H      CH.sub.2CHCH.sub.2   5,7 4-COPh CH.sub.3 4-CN 7-SO.sub.3 Na CH.sub.3      CH.sub.3 H CH.sub.2 OOCC.sub.2       H.sub.5 5 2,4-di-COOH CH.sub.3 4-NHSO.sub.2 CH.sub.3 7-OCH.sub.2      CH.sub.2 SO.sub.4 K CH.sub.3 CH.sub.3 H C.sub.6 H.sub.4-p-OOCCH.sub.3 6      4-OOCCH.sub.3 CH.sub.3 7-CH.sub.3 7-OCH.sub.2 CH.sub.2 SO.sub.4       NH(Et).sub.3 CH.sub.3 CH.sub.3 H C.sub.6       H.sub.104-CH.sub.3 6 4-NHCOCH.sub.3 CH.sub.3 7-OCH.sub.3 7-CH.sub.3      CH.sub.3 H H CH.sub.2 CH.sub.2 (C.sub.4 H.sub.4 O.sub.2 N) 6 4-NHCOPh      CH.sub.3 4-Ph 7-Ph CH.sub.3 H H CH.sub.2 CH.sub.2 NO.sub.2 4 4-C.sub.2      H.sub.5 CH.sub.3 H 7-NO.sub.2 CH.sub.3 H H C.sub.6 H.sub.4-p-NO.sub.2 6      4-Ph H H 7-OCH.sub.3 CH.sub.3 H H CH.sub.2 NHOCCH.sub. 3 6 2,5-di-Cl H      4-SO.sub.3 Na 7-NHCOCH.sub.3 CH.sub.3 H H CH.sub.2 NHSO.sub.2 CH.sub.3 6      2-Cl4-SO.sub.2 CH.sub.3 H 4-SO.sub.3 Na 7-NHSO.sub.2 CH.sub.3 CH.sub.3 H      H C.sub.6 H.sub.4-p-NHOCCH.sub.3 6 4-NHSO.sub.2 CH.sub.3 H 7-OCH.sub.2      CH.sub.2 SO.sub.4 K 7-COOCH.sub.3 CH.sub.3 C.sub.2 H.sub.5 C.sub.2      H.sub.5 C.sub.6 H.sub.4-p-NHSO.sub.2       CH.sub.3 6 4-COOCH.sub.3 H 7-OCH.sub.2 CH.sub.2 SO.sub.4 K 7-COOH H H H      C.sub.6 H.sub.104-NHOCCH.sub.3 6 2-OCH.sub.3 C.sub.2 H.sub.5 4-NHCOPh      7-Cl CH.sub.3 CH.sub.3 CH.sub.3 CH.sub.2 CH.sub.2 Cl 5 4-OC.sub.2      H.sub.5 C.sub.2 H.sub.5 4-NHCOPh 5,7-di-Br CH.sub.3 CH.sub.3 H C.sub.6      H.sub.4-p-Br 6 4-SO.sub.3 Na C.sub.2 H.sub.5 7-NHCOCH.sub.3 5,7-di-Br      CH.sub.3 CH.sub.3 H C.sub.6 H.sub.4-p-CN 6 2-SO.sub.3 Na C.sub.2 H.sub.5      7-OOCC.sub.2 H.sub.5 5-OCH.sub.37-NHCOCH.sub.3 CH.sub.3 CH.sub.3 H      CH.sub.2 CH.sub.2 CN 7 2-OCH.sub.34-SO.sub.3 K H 4-COOH 7-CH.sub.2      OOCCH.sub.3 CH.sub.3 CH.sub.3 H CH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 6      4-OCH.sub.2 CH.sub.2 OSO.sub.3 K H H 7-CH.sub.2 Cl CH.sub.3 CH.sub.3 H      CH.sub.2 CH.sub.2 OCH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 6 2-SO.sub.3      Na5-Cl H H 7-CN CH.sub.3 H H CH.sub.2 Ph 6 4-Cl H 7-SO.sub.2 CH.sub.3      7-OOCCH.sub.3 CH.sub.3 H H CH.sub.2 C.sub.6 H.sub.11 6 4-OH H 7-CF.sub.3      5-COOH CH.sub.3 H H C.sub.6 H.sub.4-o-OH 6 4-CH.sub.2 OOCCH.sub.3      C.sub.3 H.sub.7n 7-COOCH.sub.3 5-OH CH.sub.3 H H CH.sub.2 CH.sub.2 OH 6      4-SO.sub.3 K C.sub.3 H.sub.7n 7-CHO 5-CH.sub.2 CHCH.sub.2 CH.sub.3 H H      CH.sub.2 CH.sub.2SO.sub.3 K   4,6 4-OPh H 7-CONH.sub.2 7-CH.sub.3      CH.sub.3 H H C.sub.6 H.sub.4-p-OSO.sub.3 K 6 4-NO.sub.2 H 7-CONHCH.sub.3      7-COCH.sub.3 CH.sub.3 C.sub.2 H.sub.5 C.sub.2 H.sub.5 CH.sub. 2 OPh 6      5-CN H 7-CH.sub.2 Ph 7-OCH.sub.3 H H H CH.sub.2 SO.sub.2       NHPh 6 4-COCH.sub.3 H 7-CH.sub.2 SO.sub.3 K 7-SO.sub.3 Na CH.sub.3      CH.sub.3 CH.sub.3 CH.sub.2 SO.sub.2 NHCH.sub.3 6 5-CH.sub.3 H 7-CH.sub.2      OSO.sub.3 K 7-OCH.sub.2 CH.sub.2 SO.sub.4 K CH.sub.3 CH.sub.3 H C.sub.6      H.sub.4-p-SO.sub.2 NHCH.sub.3 6 5-Ph H 7-C.sub.6 H.sub.4-p-SO.sub.3 K      7-OCH.sub.2 CH.sub.2 SO.sub.3 K CH.sub.3 CH.sub.3 H CH.sub.2 COOCH.sub.3      6 5-OCH.sub.3 H 7-CH.sub.2 CH.sub.2 OH 7-CH.sub.3 CH.sub.3 CH.sub.3 H      CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2 6 4,5-di-Br H 7-CH.sub.2 Cl 7-Ph      CH.sub.3 CH.sub.3 H C.sub.6 H.sub.4-p-NHCOOCH.sub.3 6 5-COOH C.sub.4      H.sub.9n 7-C.sub.6 H.sub.4-p-Br 7-NO.sub.2 H H H CH.sub.2 CH.sub.2      CONH.sub.2 6 H H H 7-OCH.sub.3 CH.sub.3 CH.sub.3 CH.sub.3 C.sub.6      H.sub.4-p-CONHCH.sub.3 6 4-NO.sub.2 H 4-COCH.sub.3 7-NHCOCH.sub.3      CH.sub.3 CH.sub.3 H C.sub.6 H.sub.4-p-SCH.sub.3 6 4-CN H 4-NO.sub.2      7-NHSO.sub.2 CH.sub.3 CH.sub.3 CH.sub.3 H CH.sub.2 CH.sub.2 SCH.sub.3 6      5-COCH.sub.3 H 4-Cl 7-COOCH.sub.3 CH.sub.3 CH.sub.3 H CH.sub.2C.sub.6      H.sub.4-p-SCH.sub.3 6 4-COPh CH.sub.3 4-CN 7-COOH CH.sub.3 CH.sub.3 H      CH.sub.2 SO.sub.2 C.sub.2 H.sub.5 6 2,4-di-COOH CH.sub.3 4-NHSO.sub.2      CH.sub.3 7-Cl CH.sub.3 CH.sub.3 H CH.sub.2 SO.sub.2 Ph 6 4-OOCCH.sub.3      CH.sub.3 7-CH.sub.3 5,7-di-Br CH.sub.3 H H CH.sub.2 CH.sub.2 OSO.sub.3 K      6 4-NHCOCH.sub.3 CH.sub.3 7-OCH.sub.3 5,7-di-Br CH.sub.3 H H C.sub.6      H.sub.4-p-OSO.sub.3 K 6 4-NHCOPh CH.sub.3 4-Ph 5-OCH.sub.37-NHCOCH.sub.3      CH.sub.3 H H CH.sub.2 (C.sub.8 H.sub.4 O.sub.2 N) 5 4-CH.sub.2       CHCH.sub.2 H H 7-NHCOCH.sub.3 C.sub.2 H.sub.5 H H C.sub.2 H.sub.5 6 H      CH.sub.3 H 7-OCPh C.sub.2 H.sub.5 H H C.sub.2 H.sub.5   6,7 4-CONH.sub.2      H H 7-CH.sub.2 CONHCH.sub.3 H H H H 6 3-SO.sub.2 NH.sub.2 H 4-COCH.sub.3      7-CH.sub.3       CON(CH.sub.3).sub.2 CH.sub.3 CH.sub.3 CH.sub.3 Ph 6 4-SO.sub.2       NHCH.sub.3 H 4-NO.sub.2 7-CH.sub.2 CH.sub.2 OCH.sub.2 CH.sub.2 OC.sub.2      H.sub.5 CH.sub.3 CH.sub.3 H C.sub.6 H.sub.11 6 4-SO.sub.2 N(C.sub.2      H.sub.5).sub.2 H 4-Cl 7-CH.sub.2 SC.sub.2 H.sub.5 CH.sub.3 CH.sub.3 H      CH.sub.2CHCH.sub.2 7 4-SO.sub.3 C.sub.6 H.sub.5 CH.sub.3 4-CN 7-CH.sub.2      SC.sub.6 H.sub.5 CH.sub.3 CH.sub.3 H CH.sub.2 OOCC.sub.2 H.sub.5 5      4-SCH.sub.3 CH.sub.3 4-NHSO.sub.2 CH.sub.3 7-CH.sub.2 SO.sub.2 C.sub.2      H.sub.5 CH.sub.3 CH.sub.3 H C.sub.6 H.sub.4-p-OOCCH.sub.3 6 2,4-di-SCN      CH.sub.3 7-CH.sub.3 7-CH.sub.2 SO.sub.2 C.sub.6 H.sub.5 CH.sub.3      CH.sub.3 H C.sub.6 H.sub.104-CH.sub.3 6 4-SO.sub.2 C.sub.6 H.sub.5      CH.sub.3 7-OCH.sub.3 7-C.sub.6 H.sub.3- o,-p-di-CN CH.sub.3 H H CH.sub.2      CH.sub.2(C.sub.4 H.sub.4 O.sub.2 N) 6 2-CHO4-CN CH.sub.3 4-Ph 7-C.sub.6      H.sub.2-o,.sub.--m,-p-tri-Cl CH.sub.3 H H CH.sub.2 CH.sub.2 NO.sub.2 4      4-CONHC.sub.2 H.sub.5 CH.sub.3 H 5,7-di-OSO.sub.3 NH(CH.sub.3).sub.3      CH.sub.3 H H C.sub.6 H.sub.4-p-NO.sub.2 6 4-CON(C.sub.2 H.sub.5).sub.2 H      H 5,7-di-OSO.sub.3 Na CH.sub.3 H H CH.sub.2 NHOCCH.sub.3 6 3-C.sub.6      H.sub.11 H 4-SO.sub.3 Na 5,7-di-SO.sub.3 NH(CH.sub.3).sub.3 CH.sub.3 H H      CH.sub.2 NHSO.sub.2 CH.sub.3 6 3-SC.sub.6 H.sub.5 H 4-SO.sub.3 Na      7-OSO.sub.3 NH(CH.sub.3).sub.3 CH.sub.3 H H C.sub.6       H.sub.4-p-NHOCCH.sub.3 6 4-NHSO.sub.2 C.sub.6 H.sub.5 H 7-OCH.sub.2      CH.sub.2 SO.sub.4 K 5,7-di-OSO.sub.3 Na CH.sub.3 C.sub.2 H.sub.5 C.sub.2      H.sub.5 C.sub.6 H.sub.4-p-NHSO.sub.2 CH.sub.3 6 4-SC.sub.6 H.sub. 11 H      7-OCH.sub.2 CH.sub.2 SO.sub.4 K 7-SC.sub.6 H.sub.11 H H H C.sub.6      H.sub.104-NHOCCH.sub.3 6 4-C.sub.6 H.sub.4-p-CH.sub.3 C.sub.2 H.sub.5      4-NHCOPh 7-C.sub.6 H.sub.4-p-CH.sub.3 CH.sub.3 CH.sub.3 CH.sub.3      CH.sub.2 CH.sub.2 Cl 5 4-C.sub.6 H.sub.4-p-CH.sub.2 CHCH.sub.2 C.sub.2      H.sub.5 4-NHCOPh 7-C.sub.6 H.sub.4p-CH.sub.2 CHCH.sub.2 CH.sub.3      CH.sub.3 H C.sub.6 H.sub.4-p-Br 6 4-OCH.sub.2 CH.sub.2 NO.sub.2 C.sub.2      H.sub.5 7-NHCOCH.sub.3 7-OCH.sub.2 CH.sub.2 NO.sub.2 CH.sub.3 CH.sub.3 H      C.sub.6 H.sub.4-p-CN 6 2-CH.sub.2 NHCOCH.sub.3 C.sub.2       H.sub.5 7-OOCC.sub.2 H.sub.5 7-CH.sub.2 NHCOCH.sub.3 CH.sub.3 CH.sub.3      H CH.sub.2 CH.sub.2 CN 7 4-CH.sub.2 NHSO.sub.2 C.sub.2 H.sub.5 H 4-COOH      7-CH.sub.2 NHSO.sub.2 C.sub.2 H.sub.5 CH.sub.3 CH.sub.3 H CH.sub.2      CH.sub.2 OC.sub.2 H.sub.5   6,7 4-CH.sub.2 CH.sub.2 Cl H H 7-CH.sub.2      CH.sub.2 Cl CH.sub.3 CH.sub.3 H CH.sub.2 CH.sub.2 OCH.sub.2 CH.sub.2      OC.sub.2 H.sub.5 6 2,6-di-CH.sub.2 CN H H 5,7-di-CH.sub.2 CN CH.sub.3 H      H CH.sub.2 Ph 6 4-CH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 H 7-SO.sub.2      CH.sub.3 7-CH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 CH.sub.3 H H CH.sub.2      C.sub.6 H.sub.11 6 4-CH.sub.2 C.sub.6 H.sub.5 H 4-CH.sub.2 C.sub.6      H.sub.5 7-COOH CH.sub.3 H H C.sub.6 H.sub.4-o-OH 6 4-CH.sub.2 C.sub.6      H.sub.11 C.sub.3 H.sub.7n 7-COOCH.sub.3 7-CH.sub.2 C.sub.6 H.sub.11      CH.sub.3 H H CH.sub.2 CH.sub.2 OH 6 4-CH.sub.2 CH(OH)CH.sub.2 OH C.sub.3      H.sub.7n 7-CHO 7-CH.sub.2 CH(OH)CH.sub.2 OH CH.sub.3 H H CH.sub.2      CH.sub.2SO.sub.3 K 6 4-CH.sub.2 CH.sub.2SO.sub.3 K H 7-CONH.sub.2      7-CH.sub.2 CH.sub.2SO.sub.3 K CH.sub.3 H H C.sub.6 H.sub.4p-OSO.sub.3 K      6 4-CH.sub.2 OC.sub.6 H.sub.5 H 7-CONHCH.sub.3 7-CH.sub.2 OC.sub. 6      H.sub.5 CH.sub.3 C.sub.2 H.sub.5 C.sub.2 H.sub.5 CH.sub.2       OPh 6 4-CH.sub.2 OOCC.sub.6 H.sub.5 H 7-CH.sub.2 Ph 7-CH.sub.2       OOCC.sub.6 H.sub.5 H H H CH.sub.2 SO.sub.2 NHPh 6 5-CH.sub.2       COOCH.sub.3 H 7-CH.sub.2 SO.sub.3 K 7-CH.sub.2 COOCH.sub.3 CH.sub.3      CH.sub.3 CH.sub.3 CH.sub.2 SO.sub.2 NHCH.sub.3 6 4-C.sub.6       H.sub.4-p-SO.sub.2 N(C.sub.2 H.sub.5).sub.2 H 7-CH.sub.2 OSO.sub.3 K      7-C.sub.6 H.sub.4-p-SO.sub.2 N(C.sub.2 H.sub.5).sub.2 CH.sub.3 CH.sub.3      H C.sub.6 H.sub.4-p-SO.sub.2 NHCH.sub.3 6 4-CH.sub.2 CH.sub.2       NHCOOCH.sub.3 H 7-C.sub.6 H.sub.4p-SO.sub.3 K 7-CH.sub.2 CH.sub.2      NHCOOCH.sub.3 CH.sub.3 CH.sub.3 H CH.sub.2 COOCH.sub.3 6 4-CH.sub.2      NHCONHCH.sub.3 H 7-CH.sub.2 CH.sub.2 OH 7-CH.sub.2 NHCONHCH.sub.3      CH.sub.3 CH.sub.3 H CH.sub.2 SO.sub.2       N(CH.sub.3).sub.2

    TABLE 3       ##STR8##        Cinnamoyl       Group Position R.sub.1 on D R.sub.5 Substituents on A      R.sub.1 on C R.sub.3 R.sub.7        6 H H H H H H 6 4-NO.sub.2 H 4-COCH.sub.3 6-CH.sub.3 CH.sub.3 Ph 6      4-CN H 4-NO.sub.2 6-COCH.sub.3 C.sub. 2 H.sub.5 C.sub.6 H.sub.11 6      5-COCH.sub.3 H 4-Cl 6-OCH.sub.3 H CH.sub.2CHCH.sub.2 7 4-COPh CH.sub.3      4-CN 6-SO.sub.3 Na H CH.sub.2 OOCC.sub.2 H.sub.5 5 2,4-di-COOH CH.sub.3      4-NHSO.sub.2 CH.sub.3 6-OCH.sub.2 CH.sub.2 SO.sub.4 K H C.sub.6       H.sub.4-p-OOCCH.sub.3 6 4-OOCCH.sub.3 CH.sub.3 7-CH.sub.3 6-OCH.sub.2      CH.sub.2 SO.sub.4 K H C.sub.6 H.sub.104-CH.sub.3 6 4-NHCOCH.sub.3      CH.sub.3 7-OCH.sub.3 6-CH.sub.3 H CH.sub.2 CH.sub.2 (C.sub.4 H.sub.4      O.sub.2 N)   6,7 4-NHCOPh CH.sub.3 4-Ph 6-Ph CH.sub.3 CH.sub.2 CH.sub.2      NO.sub.2 4 4-C.sub.2 H.sub.5 CH.sub.3 H 6-NO.sub.2 CH.sub.3 C.sub.6      H.sub.4-p-NO.sub.2 6 4-Ph H H 6-OCH.sub.3 CH.sub.3 CH.sub.2 NHOCCH.sub.3 6       4-CH.sub.2 CONH.sub.2 H 7-CH.sub.2 Cl 7-CH.sub.2 CONH.sub.2 CH.sub.3      CH.sub.3 H C.sub.6 H.sub.4-p-NHCOOCH.sub.3 6 5-CH.sub.2 CONHCH.sub.3      C.sub.4 H.sub.9n 7-C.sub.6 H.sub.4-p-Br 7-CONH.sub.2 H H H CH.sub.2      CH.sub.2 CONH.sub.2 6 4-CH.sub.2 CON(CH.sub.3).sub.2 H H 7-SO.sub.2      NH.sub.2 CH.sub.3 CH.sub.3 CH.sub.3 C.sub.6 H.sub.4-p-CONHCH.sub.3 6      4-CH.sub.2 CH.sub.2 OCH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 H 4-COCH.sub.3      7-SO.sub.2 NHCH.sub.3 CH.sub.3 CH.sub.3 H C.sub.6 H.sub.4-p-SCH.sub.3 6      4-CH.sub.2 SC.sub.2 H.sub.5 H 4-NO.sub.2 7-SO.sub.2 N(C.sub.2       H.sub.5).sub.2 CH.sub.3 CH.sub.3 H CH.sub.2 CH.sub.2 SCH.sub.3   5,6      5-CH.sub.2 SC.sub.6 H.sub.5 H 4-Cl 7-SO.sub.3 C.sub.6 H.sub.5 CH.sub.3      CH.sub.3 H CH.sub.2C.sub.6 H.sub.4-p-SCH.sub.3 6 4-CH.sub.2 SO.sub.2      C.sub.2 H.sub.5 CH.sub.3 4-CN 7-SCH.sub.3 CH.sub.3 CH.sub.3 H CH.sub.2      SO.sub.2 C.sub.2 H.sub.5 6 2,4-di-CH.sub.2 SO.sub.2 C.sub.6 H.sub.5      CH.sub.3 4-NHSO.sub.2 CH.sub.3 5,7-di-SCN CH.sub.3 CH.sub.3 H CH.sub.2      SO.sub.2 Ph 6 4-C.sub.6       H.sub. 3-o,-p-di-CN CH.sub.3 7-CH.sub.3 7-SO.sub.2 C.sub.6 H.sub.5      CH.sub.3 H H CH.sub.2 CH.sub.2 OSO.sub.3 K 6 4-C.sub.6       H.sub.2-o,.sub.--m,-p-tri-Cl CH.sub.3 7-OCH.sub.3 5-CHO7-CN CH.sub.3 H      H C.sub.6 H.sub.4-p-OSO.sub.3 K 6 2,6-di-OSO.sub.3 Na CH.sub.3 4-Ph      7-CONHC.sub.2 H.sub.5 CH.sub.3 H H CH.sub.2 (C.sub.8 H.sub.4 O.sub.2 N)      6 H H 7-CH.sub.2 (C.sub.4 H.sub.4 O.sub.2 N) 7-CON(C.sub.2       H.sub.5).sub.2 CH.sub.3 H H C.sub.2 H.sub.5 6 H H 7-CH.sub.2 (C.sub.4      H.sub.3 O) 7-C.sub.6 H.sub.11 CH.sub.3 H H C.sub.2 H.sub.5 6 5-CH.sub.2      (C.sub.8 H.sub.4 O.sub.2 N) H H 7-SC.sub.6 H.sub.5 CH.sub.3 H H C.sub.2      H.sub.5 6 5-CH.sub.2 (C.sub.4 H.sub.3 O) H H 7-NHSO.sub.2 C.sub.6      H.sub.5 CH.sub.3 C.sub.2 H.sub.5 C.sub.2 H.sub.5 C.sub.2 H.sub.5 6      2,5-di-Cl H 4-SO.sub. 3 Na 6-NHCOCH.sub.3 C.sub.2 H.sub.5 CH.sub.2      NHSO.sub.2 CH.sub.3 6 2-Cl4-SO.sub.2 CH.sub.3 H 4-SO.sub.3       Na 6-NHSO.sub.2 CH.sub.3 CH.sub.3 C.sub.6 H.sub.4-p-NHOCCH.sub.3 6      4-NHSO.sub.2 CH.sub.3 H 7-OCH.sub.2 CH.sub.2 SO.sub.4 K 6-COOCH.sub.3      CH.sub.3 C.sub.6 H.sub.4-p-NHSO.sub.2 CH.sub.3 6 4-COOCH.sub.3 H      7-OCH.sub.2 CH.sub.2 SO.sub.4 K 6-COOH H C.sub.6 H.sub.104-NHOCCH.sub.3      6 2-OCH.sub.3 C.sub.2 H.sub.5 4-NHCOPh 6-Cl CH.sub.3 CH.sub.2 CH.sub.2      Cl 5 4-OC.sub.2 H.sub.5 C.sub.2 H.sub.5 4-NHCOPh 5,6-di-Br C.sub.2      H.sub.5 C.sub.6 H.sub.4-p-Br 6 4-SO.sub.3 Na C.sub.2       H.sub.5 7-NHCOCH.sub.3 5,6-di-Br H C.sub.6 H.sub.4-p-CN 6 2-SO.sub.3 Na      C.sub.2 H.sub.5 7-OOCC.sub.2 H.sub.5 5-OCH.sub.36-NHCOCH.sub.3 H      CH.sub.2 CH.sub.2 CN 7 2-OCH.sub.34-SO.sub.3 K H 4-COOH 6-CH.sub.2      OOCCH.sub.3 H CH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 6 4-OCH.sub.2 CH.sub.2      OSO.sub.3 K H H 6-CH.sub.2 Cl H CH.sub.2 CH.sub.2 OCH.sub.2 CH.sub.2      OC.sub.2 H.sub.5   6,7 2-SO.sub.3 Na5-Cl H H 6-CN H CH.sub.2 Ph 6 4-Cl H      7-SO.sub.2 CH.sub.3 6-OOCCH.sub.3 CH.sub.3 CH.sub.2 C.sub.6 H.sub.11 6      4-OH H 7-CF.sub.3 5-COOH CH.sub.3 C.sub.6 H.sub.4o-OH 6 4-CH.sub.2      OOCCH.sub.3 C.sub.3 H.sub.7n 7-COOCH.sub.3 5-OH CH.sub.3 CH.sub.2      CH.sub.2 OH 6 4-SO.sub.3 K C.sub.3 H.sub.7n 7-CHO 5-CH.sub.2 CHCH.sub.2      C.sub.2 H.sub.5 CH.sub.2 CH.sub.2SO.sub.3 K 6 4-OPh H 7-CONH.sub.2      6-CH.sub.3 CH.sub.3 C.sub.6 H.sub.4-p-OSO.sub.3 K 6 4-NO.sub.2 H      7-CONHCH.sub.3 6-COCH.sub.3 CH.sub.3 CH.sub.2 OPh 6 5-CN H 7-CH.sub.2 Ph      6-OCH.sub.3 H CH.sub.2 SO.sub.2 NHPh 6 4-COCH.sub.3 H 7-CH.sub.2      SO.sub.3 K 6-SO.sub.3 Na CH.sub.3 CH.sub.2 SO.sub.2 NHCH.sub.3 6      5-CH.sub.3 H 7-CH.sub.2 OSO.sub.3 K 6-OCH.sub.2 CH.sub.2 SO.sub.4 K H      C.sub.6 H.sub.4- p-SO.sub.2 NHCH.sub.3 6 5-Ph H 7-C.sub.6       H.sub.4-p-SO.sub.3 K 6-OCH.sub.2 CH.sub.2 SO.sub.3 K H CH.sub.2      COOCH.sub.3 6 5-OCH.sub.3 H 7-CH.sub.2 CH.sub.2 OH 6-CH.sub.3 H CH.sub.2      SO.sub.2 N(CH.sub.3).sub.2 6 4,5-di-Br H 7-CH.sub.2 Cl 6-Ph H C.sub.6      H.sub.4p-NHCOOCH.sub.3 6 5-COOH C.sub.4 H.sub.9n 7-C.sub.6 H.sub.4-p-Br      6-NO.sub.2 C.sub.2 H.sub.5 CH.sub.2 CH.sub.2       CONH.sub.2 6 H H H 6-OCH.sub.3 C.sub.2 H.sub.5 C.sub.6       H.sub.4p-CONHCH.sub.3 6 4-NO.sub.2 H 4-COCH.sub.3 6-NHCOCH.sub.3      CH.sub.3 C.sub.6 H.sub.4-p-SCH.sub.3 6 4-CN H 4-NO.sub.2 6-NHSO.sub.2      CH.sub.3 C.sub.3 H.sub.7n CH.sub.2 CH.sub.2 SCH.sub.3 6 5-COCH.sub.3 H      4-Cl 6-COOCH.sub.3 H CH.sub.2C.sub.6 H.sub.4-p-SCH.sub.3 6 4-COPh      CH.sub.3 4-CN 6-COOH CH.sub.3 CH.sub.2 SO.sub.2 C.sub.2 H.sub.5 6      2,4-di-COOH CH.sub.3 4-NHSO.sub.2 CH.sub.3 8-Cl H CH.sub.2 SO.sub.2 Ph 6      4-OOCCH.sub.3 CH.sub.3 7-CH.sub.3 5,6-di-Br H CH.sub.2 CH.sub.2       OSO.sub.3 K 6 4-NHCOCH.sub.3 CH.sub.3 7-OCH.sub.3 5,6-di-Br H C.sub.6      H.sub.4-p-OSO.sub.3 K 6 4-NHCOPh CH.sub.3 4-Ph 5-OCH.sub.36-NHCOCH.sub.3      H CH.sub.2 (C.sub.8 H.sub.4 O.sub.2 N) 5 4-CH.sub.2 CHCH.sub.2 H H      6-NHCOCH.sub.3 C.sub.2 H.sub.5 C.sub.2 H.sub.5   6,7 H CH.sub.3 H 6-OCPh      C.sub.2 H.sub.5 C.sub.2 H.sub.5 6 4-CONH.sub.2 H H 6-CH.sub.2       CONHCH.sub.3 H H 6 3-SO.sub.2 NH.sub.2 H 4-COCH.sub.3 6-CH.sub.2      CON(CH.sub.3).sub.2 CH.sub.3 Ph 6 4-SO.sub.2 NHCH.sub.3 H 4-NO.sub.2      6-CH.sub.2 CH.sub.2 OCH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 C.sub.2 H.sub.5      C.sub.6 H.sub.11 6 4-SO.sub.2 N(C.sub.2 H.sub.5).sub.2 H 4-Cl 6-CH.sub.2      SC.sub.2 H.sub.5 H CH.sub.2CHCH.sub.2 7 4-SO.sub.3 C.sub.6 H.sub.5      CH.sub.3 4-CN 6-CH.sub.2 SC.sub.6 H.sub.5 H CH.sub.2 OOCC.sub.2 H.sub.5      5 4-SCH.sub.3 CH.sub.3 4-NHSO.sub.2 CH.sub.3 6-CH.sub.2 SO.sub.2 C.sub.2      H.sub.5 H C.sub.6 H.sub.4-p-OOCCH.sub.3 6 2,4-di-SCN CH.sub.3 7-CH.sub.3      6-CH.sub.2 SO.sub.2 C.sub.6 H.sub.5 H C.sub.6 H.sub.104-CH.sub.3 6      4-SO.sub.2 C.sub.6 H.sub.5 CH.sub.3 7-OCH.sub.3 6-C.sub.6       H.sub.3-o,-p-di-CN H CH.sub.2 CH.sub.2(C.sub.4 H.sub.4 O.sub.2 N) 6      2-CHO4-CN CH.sub.3 4-Ph 6-C.sub.6 H.sub.2-o,.sub.--m,-p-tri-Cl CH.sub.3      CH.sub.2 CH.sub.2 NO.sub.2 4 4-CONHC.sub.2       H.sub.5 CH.sub.3 H 6,8-di-OSO.sub.3 NH(CH.sub.3).sub.3 CH.sub.3 C.sub.6      H.sub.4-p-NO.sub.2 6 4-CON(C.sub.2 H.sub.5).sub.2 H H 5,6-di-OSO.sub.3      Na CH.sub.3 CH.sub.2 NHOCCH.sub.3 6 3-C.sub.6 H.sub.11 H 4-SO.sub.3 Na      5,6-di-OSO.sub.3 Na C.sub.2 H.sub.5 CH.sub.2 NHSO.sub.2 CH.sub.3 6      3-SC.sub.6 H.sub.5 H 4-SO.sub.3 Na 5,6-di-SO.sub.3 NH(CH.sub.3).sub.3      CH.sub.3 C.sub.6 H.sub.4-p-NHOCCH.sub.3 6 4-NHSO.sub.2 C.sub.6 H.sub.5 H      7-OCH.sub.2 CH.sub.2 SO.sub.4 K 5,6-di-OSO.sub.3 Na CH.sub.3 C.sub.6      H.sub.4 -p-NHSO.sub.2 CH.sub.3 6 4-SC.sub.6 H.sub.11 H 7-OCH.sub.2      CH.sub.2 SO.sub.4 K 6-SC.sub.6 H.sub.11 H C.sub.6 H.sub.104-NHOCCH.sub.3      6 4-C.sub.6 H.sub.4p-CH.sub.3 C.sub.2 H.sub.5 4-NHCOPh 6-C.sub.6         p      H.sub.4--CH.sub.3 CH.sub.3 CH.sub.2 CH.sub.2 Cl 5 4-C.sub.6       H.sub.4-p-CH.sub.2 CHCH.sub.2 C.sub.2 H.sub.5 4-NHCOPh 6-C.sub.6      H.sub.4-p-CH.sub.2 CHCH.sub.2 C.sub.2 H.sub.5 C.sub.6 H.sub.4-p-Br 6      4-OCH.sub.2 CH.sub.2 NO.sub.2 C.sub.2 H.sub.5 7-NHCOCH.sub.3 6-OCH.sub.2      CH.sub.2 NO.sub.2 H C.sub.6 H.sub.4-p-CN 6 2-CH.sub.2 NHCOCH.sub.3      C.sub.2 H.sub.5 7-OOCC.sub.2 H.sub.5 6-CH.sub.2 NHCOCH.sub.3 H CH.sub.2      CH.sub.2 CN 7 4-CH.sub.2 NHSO.sub.2 C.sub.2 H.sub.5 H 4-COOH 6-CH.sub.2      NHSO.sub.2 C.sub.2 H.sub. 5 H CH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 6      4-CH.sub.2 CH.sub.2 Cl H H 6-CH.sub.2 CH.sub.2 Cl H CH.sub.2 CH.sub.2      OCH.sub.2 CH.sub.2 OC.sub.2 H.sub.5   6,7 2,6-di-CH.sub.2 CN H H      5,6-di-CH.sub.2 CN H CH.sub.2 Ph 6 4-CH.sub.2 CH.sub.2 OC.sub.2 H.sub.5      H 7-SO.sub.2 CH.sub.3 6-CH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 CH.sub.3      CH.sub.2 C.sub.6 H.sub.11 6 4-CH.sub.2 C.sub.6 H.sub.5 H 4-CH.sub.2      C.sub.6 H.sub.5 6-COOH CH.sub.3 C.sub.6 H.sub.4-o-OH 6 4-CH.sub.2      C.sub.6 H.sub.11 C.sub.3 H.sub.7n 7-COOCH.sub.3 6-CH.sub.2 C.sub.6      H.sub.11 CH.sub.3 CH.sub.2 CH.sub.2 OH 6 4-CH.sub.2 CH(OH)CH.sub.2 OH      C.sub.3 H.sub.7n 7-CHO 6-CH.sub.2 CH(OH)CH.sub.2 OH C.sub.2 H.sub.5      CH.sub.2 CH.sub.2SO.sub.3 K 6 4-CH.sub.2 CH.sub.2SO.sub.3       K H 7-CONH.sub.2 6-CH.sub.2 CH.sub.2SO.sub.3 K CH.sub.3 C.sub.6         p      H.sub.4--OSO.sub.3 K 6 4-CH.sub.2 OC.sub.6 H.sub.5 H 7-CONHCH.sub. 3      6-CH.sub.2 OC.sub.6 H.sub.5 CH.sub.3 CH.sub.2 OPh 6 4-CH.sub.2       OOCC.sub.6 H.sub.5 H 7-CH.sub.2 Ph 6-CH.sub.2 OOCC.sub.6 H.sub.5 H      CH.sub.2 SO.sub.2 NHPh 6 5-CH.sub.2 COOCH.sub.3 H 7-CH.sub.2 SO.sub.3 K      5-CH.sub.2 COOCH.sub.3 CH.sub.3 CH.sub.2 SO.sub.2 NHCH.sub.3 6 4-C.sub.6      H.sub.4-p-SO.sub.2 N(C.sub.2 H.sub.5).sub.2 H 7-CH.sub.2 OSO.sub.3 K      6-C.sub.6 H.sub.4-p-SO.sub.2 N(C.sub.2 H.sub.5).sub.2 H C.sub.6       H.sub.4-p-SO.sub.2 NHCH.sub.3 6 4-CH.sub.2 CH.sub.2 NHCOOCH.sub.3 H      7-C.sub.6 H.sub.4-p-SO.sub.3 K 6-CH.sub.2 CH.sub.2 NHCOOCH.sub.3 H      CH.sub.2 COOCH.sub.3 6 4-CH.sub.2 NHCONHCH.sub.3 H 7-CH.sub.2 CH.sub.2      OH 6-CH.sub.2 NHCONHCH.sub.3 H CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2 6      4-CH.sub.2 CONH.sub.2 H 7-CH.sub.2 Cl 6-CH.sub.2 CONH.sub.2 H C.sub.6      H-p-NHCOOCH.sub.3 6 5-CH.sub.2 CONHCH.sub.3 C.sub.4 H.sub.9n 7-C.sub.6      H.sub. 4-p-Br 6-CONH.sub.2 C.sub.2 H.sub.5 CH.sub.2 CH.sub.2 CONH.sub.2      6 4-CH.sub.2 CON(CH.sub.3).sub.2 H H 6-SO.sub.2 NH.sub.2 C.sub.2 H.sub.5      C.sub.6 H.sub.4-p-CONHCH.sub.3 6 4-CH.sub.2 CH.sub.2 OCH.sub.2 CH.sub.2      OC.sub.2 H.sub.5 H 4-COCH.sub.3 6-SO.sub.2 NHCH.sub.3 CH.sub.3 C.sub.6      H.sub.4-p-SCH.sub.3 6 4-CH.sub.2 SC.sub.2       H.sub.5 H 4-NO.sub.2 6-SO.sub.2 N(C.sub.2 H.sub.5).sub.2 C.sub.3        n      H.sub.7 CH.sub.2 CH.sub.2 SCH.sub.3 6 5-CH.sub.2 SC.sub.6 H.sub.5 H 4-Cl      6-SO.sub.3 C.sub.6 H.sub.5 H CH.sub.2C.sub.6 H.sub.4-p-SCH.sub.3 6      4-CH.sub.2 SO.sub.2 C.sub.2 H.sub.5 CH.sub.3 4-CN 6-SCH.sub.3 CH.sub.3      CH.sub.2 SO.sub.2 C.sub.2 H.sub.5   5,6 2,4-di-CH.sub.2 SO.sub.2 C.sub.6      H.sub.5 CH.sub.3 4-NHSO.sub.2 CH.sub.3 5,6-di-SCN H CH.sub.2 SO.sub.2 Ph      6 4-C.sub.6 H.sub.3-o,-p-di-CN CH.sub.3 7-CH.sub.3 6-SO.sub.2 C.sub.6      H.sub.5 H CH.sub.2 CH.sub.2 OSO.sub.3 K 6 4-C.sub.6       H.sub.2-o,.sub.--m,-p-tri-Cl CH.sub.3 7-OCH.sub.3 5-CHO6-CN H C.sub.6      H.sub.4-p-OSO.sub.3 K 6 2,6-di-OSO.sub.3 Na CH.sub.3 4-Ph 6-CONHC.sub.2      H.sub.5 H CH.sub.2(C.sub.8 H.sub.4 O.sub.2 N) 6 H H 7-CH.sub.2 (C.sub.4      H.sub.4 O.sub.2 N) 6-CON(C.sub.2 H.sub.5).sub.2 H C.sub.2 H.sub.5 6 H H      7-CH.sub.2 (C.sub.4 H.sub.3 O) 6-C.sub.6 H.sub.11 H C.sub.2 H.sub.5 6      5-CH.sub.2 (C.sub.8 H.sub.4 O.sub.2 N) H H 6-SC.sub.6 H.sub.5 H C.sub.2      H.sub.5 6 5-CH.sub.2 (C.sub.4 H.sub.3 O) H H 6-NHSO.sub.2 C.sub.6      H.sub.5 H C.sub.2       H.sub.5

    TABLE 4       ##STR9##        Cinnamoyl Group   Substituents    Position R.sub.1 on D R.sub.5 on B      R.sub.1 on C R.sub.2 R.sub.7        5 H H H H H H 5 4-NO.sub.2 H 4-COCH.sub.3 2-CH.sub.3 C.sub.2 H.sub.5      Ph 5 4-CN H 4-NO.sub.2 5-COCH.sub.3 C.sub.2 H.sub.5 C.sub.6 H.sub.11 5      5-COCH.sub.3 H 4-Cl 5-OCH.sub.3 H CH.sub.2CHCH.sub.2 5,7 4-COPh CH.sub.3      4-CN 5-SO.sub.3 Na H CH.sub.2 OOCC.sub.2 H.sub.5 5,6 2,4-di-COOH      CH.sub.3 4-NHSO.sub.2 CH.sub.3 5-OCH.sub.2 CH.sub.2 SO.sub.4 K H C.sub.6      H.sub.4-p-OOCCH.sub.3 6 4-OOCCH.sub.3 CH.sub.3 7-CH.sub.3 5-OCH.sub.2      CH.sub.2 SO.sub.4 K H C.sub.6 H.sub.104-CH.sub.3 6 4-NHCOCH.sub.3      CH.sub.3 7-OCH.sub.3 2-CH.sub.3 H CH.sub.2 CH.sub.2 (C.sub.4 H.sub.4      O.sub.2 N) 6 4-NHCOPh CH.sub.3 4-Ph 2-Ph CH.sub.3 CH.sub.2 CH.sub.2      NO.sub.2 6 4-C.sub.2 H.sub.5 CH.sub.3 H 2-NO.sub.2 CH.sub.3 C.sub.6      H.sub.4-p-NO.sub.2 6 4-Ph H H 2-OCH.sub.3 CH.sub.3 CH.sub.2 NHOCCH.sub.3      6 2,5-di-Cl H 4-SO.sub.3 Na 5-NHCOCH.sub.3 C.sub.2 H.sub.5 CH.sub.2      NHSO.sub.2 CH.sub.3 6 2-Cl4-SO.sub.2 CH.sub.3 H 4-SO.sub.3       Na 3-NHSO.sub.2 CH.sub.3 C.sub.2 H.sub.5 C.sub.6 H.sub.4-p-NHOCCH.sub.3      6 4-NHSO.sub.2 CH.sub.3 H 7-OCH.sub.2 CH.sub.2 SO.sub. 4 K 3-COOCH.sub.3      C.sub.2 H.sub.5 C.sub.6 H.sub.4-p-NHSO.sub.2 CH.sub.3 6 4-COOCH.sub.3 H      7-OCH.sub.2 CH.sub.2 SO.sub.4 K 3-COOH C.sub.2 H.sub.5 C.sub.6       H.sub.104-NHOCCH.sub.3 5 2-OCH.sub.3 C.sub.2 H.sub.5 4-NHCOPh 2-Cl      CH.sub.2 CH.sub.2 Cl CH.sub.2 CH.sub.2 Cl 5 4-OC.sub.2 H.sub.5 C.sub.2      H.sub.5 4-NHCOPh 2,6-di-Br C.sub.6 H.sub.4-p-Br C.sub.6 H.sub.4-p-Br 5,6      4-SO.sub.3 Na C.sub.2 H.sub.5 7-NHCOCH.sub.3 2,6-di-Br C.sub.6       H.sub.4-p-CN C.sub.6 H.sub.4-p-CN 5,6 2-SO.sub.3 Na C.sub.2 H.sub.5      7-OOCC.sub.2 H.sub.5 2-OCH.sub.35-NHCOCH.sub.3 CH.sub.2 CH.sub.2 CN      CH.sub.2 CH.sub.2 CN 5,6 2-OCH.sub.34-SO.sub.3 K H 4-COOH 2-CH.sub.2      OOCCH.sub.3 CH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 CH.sub.2 CH.sub.2      OC.sub.2 H.sub.5 5,6 4-OCH.sub.2 CH.sub.2 OSO.sub.3 K H H 2-CH.sub.2 Cl      CH.sub.2 CH.sub.2 OCH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 CH.sub.2 CH.sub.2      OCH.sub.2 CH.sub.2 OC.sub.2 H.sub. 5 5,6 2-SO.sub.3 Na5-Cl H H 2-CN      CH.sub.2 Ph CH.sub.2 Ph 5,6 4-Cl H 7-SO.sub.2 CH.sub.3 2-OOCCH.sub.3      CH.sub.2 C.sub.6 H.sub.11 CH.sub.2 C.sub.6 H.sub.11 6 4-OH H 7-CF.sub.3      5-COOH H C.sub.6 H.sub.4-o-OH 6 4-CH.sub.2 OOCCH.sub.3 C.sub.3 H.sub.7n      7-COOCH.sub.3 5-OH C.sub.2 H.sub.5 CH.sub.2 CH.sub.2 OH 6 4-SO.sub.3 K      C.sub.3 H.sub.7n 7-CHO 5-CH.sub.2 CHCH.sub.2 CH.sub.2 CH.sub.2SO.sub.3 K      CH.sub.2 CH.sub.2SO.sub.3 K 6 4-OPh H 7-CONH.sub.2 2-CH.sub.3 H C.sub.6      H.sub.4-p-OSO.sub.3 K 6 4-NO.sub.2 H 7-CONHCH.sub.3 5-COCH.sub.3 H      CH.sub.2 OPh 5 5-CN H 7-CH.sub.2 Ph 5-OCH.sub.3 H CH.sub.2 SO.sub.2 NHPh      5 4-COCH.sub.3 H 7-CH.sub.2 SO.sub.3 K 5-SO.sub.3 Na CH.sub.2 SO.sub.2      NHCH.sub.3 CH.sub.2 SO.sub.2 NHCH.sub.3 5 5-CH.sub.3 H 7-CH.sub.2      OSO.sub.3 K 5-OCH.sub.2 CH.sub.2 SO.sub.4 K H C.sub.6 H.sub.4-p-SO.sub.2      NHCH.sub. 3 5 5-Ph H 7-C.sub.6 H.sub.4-p-SO.sub.3 K 5-OCH.sub.2 CH.sub.2      SO.sub.3 K CH.sub.2 COOCH.sub.3 CH.sub.2 COOCH.sub.3 5 5-OCH.sub.3 H      7-CH.sub.2 CH.sub.2 OH 2-CH.sub.3 H CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2      5 4,5-di-Br H 7-CH.sub.2 Cl 2-Ph C.sub.2 H.sub.5 C.sub.6       H.sub.4-p-NHCOOCH.sub.3 5 5-COOH C.sub.4 H.sub.9n 7-C.sub.6       H.sub.4-p-Br 2-NO.sub.2 C.sub.2 H.sub.5 CH.sub.2 CH.sub.2 CONH.sub.2 6      H H H 2-OCH.sub.3 C.sub.2 H.sub.5 C.sub.6 H.sub.4-p-CONHCH.sub.3 6      4-NO.sub.2 H 4-COCH.sub.3 5-NHCOCH.sub.3 C.sub.2 H.sub.5 C.sub.6         p      H.sub.4--SCH.sub.3 6 4-CN H 4-NO.sub.2 3-NHSO.sub.2 CH.sub.3 CH.sub.2      CH.sub.2 SCH.sub.3 CH.sub.2 CH.sub.2 SCH.sub.3 6 5-COCH.sub.3 H 4-Cl      3-COOCH.sub.3 H CH.sub.2C.sub.6 H.sub.4-p-SCH.sub.3 6 4-COPh CH.sub.3      4-CN 3-COOH CH.sub.2 SO.sub.2 C.sub.2 H.sub.5 CH.sub.2 SO.sub.2 C.sub.2      H.sub.5 6 2,4-di-COOH CH.sub.3 4-NHSO.sub.2 CH.sub.3 2-Cl H CH.sub.2      SO.sub.2 Ph 6 4-OOCCH.sub.3 CH.sub.3 7-CH.sub.3 2,6-di-Br H CH.sub.2      CH.sub.2 OSO.sub.3 K 6 4-NHCOCH.sub.3 CH.sub.3 7-OCH.sub.3 2,6-di-Br H      C.sub.6 H.sub.4-p-OSO.sub.3       K 6,7 4-NHCOPh CH.sub.3 4-Ph 2-OCH.sub.35-NHCOCH.sub.3 H CH.sub.2      (C.sub.8 H.sub.4 O.sub.2 N) 5 4-CH.sub.2 CHCH.sub.2 H H 3-NHCOCH.sub.3      C.sub.2 H.sub.5 C.sub.2 H.sub.5 6 H CH.sub.3 H 3-OCPh C.sub.2 H.sub.5      C.sub.2 H.sub.5 6 4-CONH.sub.2 H H 5-CH.sub.2 CONHCH.sub.3 H H 6      3-SO.sub.2 NH.sub.2 H 4-COCH.sub.3 5-CH.sub.2 CON(CH.sub.3).sub.2      C.sub.2 H.sub.5 Ph 5,6 4-SO.sub.2 NHCH.sub.3 H 4-NO.sub.2 5-CH.sub.2      CH.sub.2 OCH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 C.sub.2 H.sub.5 C.sub.6      H.sub.11 6 4-SO.sub.2 N(C.sub.2 H.sub.5).sub.2 H 4-Cl 5-CH.sub.2      SC.sub.2 H.sub.5 H CH.sub.2CHCH.sub.2 7 4-SO.sub.3 C.sub.6 H.sub.5      CH.sub.3 4-CN 2-CH.sub.2 SC.sub.6 H.sub.5 H CH.sub.2 OOCC.sub.2 H.sub.5      5 4-SCH.sub.3 CH.sub.3 4-NHSO.sub.2 CH.sub.3 5-CH.sub.2 SO.sub.2 C.sub.2      H.sub.5 H C.sub.6 H.sub.4-p-OOCCH.sub.3 6 2,4-di-SCN CH.sub.3 7-CH.sub.3      5-CH.sub.2 SO.sub.2 C.sub.6 H.sub.5 H C.sub.6 H.sub.104-CH.sub.3 6      4-SO.sub.2 C.sub.6 H.sub.5 CH.sub.3 7-OCH.sub.3 5-C.sub.6       H.sub.3-o,-p-di-CN H CH.sub.2 CH.sub.2 (C.sub.4 H.sub.4 O.sub.2 N) 6      2-CHO4-CN CH.sub.3 4-Ph 5-C.sub.6 H.sub.2-o,.sub.--m,-p-triCl CH.sub.3      CH.sub.2 CH.sub.2 NO.sub.2 4 4-CONHC.sub.2       H.sub.5 CH.sub.3 H 5-OSO.sub.3 NH(CH.sub.3).sub.3 CH.sub.3 C.sub.6      H.sub.4-p-NO.sub.2 6 4-CON(C.sub.2 H.sub.5).sub.2 H H 2,6-di-OSO.sub.3      Na CH.sub.3 CH.sub.2 NHOCCH.sub.3 6 3-C.sub.6 H.sub.11 H 4-SO.sub.3 Na      2,6-di-SO.sub.3 NH(CH.sub.3).sub.3 C.sub.2 H.sub.5 CH.sub. 2 NHSO.sub.2      CH.sub.3 6,7 3-SC.sub.6 H.sub.5 H 4-SO.sub.3 Na 2,6-di-OSO.sub.3 Na      C.sub.2 H.sub.5 C.sub.6 H.sub.4-p-NHOCCH.sub.3 6 4-NHSO.sub.2 C.sub.6      H.sub.5 H 7-OCH.sub.2 CH.sub.2 SO.sub.4 K 6-OSO.sub.3 NH(CH.sub.3).sub.3      C.sub.2 H.sub.5 C.sub.6 H.sub.4-p-NHSO.sub.2 CH.sub.3 6 4-SC.sub.6      H.sub.11 H 7-OCH.sub.2 CH.sub.2 SO.sub.4 K 5-SC.sub.6 H.sub.11 C.sub.2      H.sub.5 C.sub.6 H.sub.104-NHOCCH.sub.3 6 4-C.sub.6 H.sub.4-p-CH.sub.3      C.sub.2 H.sub.5 4-NHCOPh 5-C.sub.6 H.sub.4-p-CH.sub.3 CH.sub.2 CH.sub.2      Cl CH.sub.2 CH.sub.2 Cl 5 4-C.sub.6 H.sub.4-p-CH.sub.2 CHCH.sub.2      C.sub.2 H.sub.5 4-NHCOPh 5-C.sub.6 H.sub.4-p-CH.sub.2 CHCH.sub.2 C.sub.6      H.sub.4 p-Br C.sub.6 H.sub.4-p-Br 6 4-OCH.sub.2 CH.sub.2 NO.sub.2      C.sub.2 H.sub.5 7-NHCOCH.sub.3 5-OCH.sub.2 CH.sub.2 NO.sub.2 C.sub.6      H.sub.4-p-CN C.sub.6 H.sub.4-p-CN 6 2-CH.sub.2 NHCOCH.sub.3 C.sub.2      H.sub.5 7-OOCC.sub.2 H.sub.5 2-CH.sub.2 NHCOCH.sub.3 CH.sub.2 CH.sub.2      CN CH.sub.2 CH.sub.2 CN 7 4-CH.sub.2 NHSO.sub.2 C.sub.2 H.sub.5 H 4-COOH      5-CH.sub.2 NHSO.sub.2 C.sub.2 H.sub.5 CH.sub.2 CH.sub.2 OC.sub.2 H.sub.5      CH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 6,7 4-CH.sub.2 CH.sub.2 Cl H H      5-CH.sub.2 CH.sub.2 Cl CH.sub.2 CH.sub.2 OCH.sub.2 CH.sub.2 OC.sub.2      H.sub.5 CH.sub.2 CH.sub.2 OCH.sub.2 CH.sub.2 OC.sub.2       H.sub.5 6 2,6-di-CH.sub.2 CN H H 2,6-di-CH.sub.2 CN CH.sub.2 Ph      CH.sub.2 Ph 6 4-CH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 H 7-SO.sub.2 CH.sub.3      5-CH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 CH.sub.2 C.sub.6 H.sub.11 CH.sub.2      C.sub.6 H.sub.11 6 4-CH.sub.2 C.sub.6 H.sub.5 H 4-CH.sub.2 C.sub.6      H.sub.5 5-COOH H C.sub.6 H.sub.4-o-OH 6 4-CH.sub.2 C.sub.6 H.sub.11      C.sub.3 H.sub.7n 7-COOCH.sub.3 5-CH.sub.2 C.sub.6 H.sub.11 C.sub.2      H.sub.5 CH.sub.2 CH.sub.2 OH 6 4-CH.sub.2 CH(OH)CH.sub.2 OH C.sub.3      H.sub.7n 7-CHO 5-CH.sub.2 CH(OH)CH.sub.2 OH CH.sub.2 CH.sub.2SO.sub.3 K      CH.sub.2 CH.sub.2SO.sub.3 K 6 4-CH.sub.2 CH.sub.2SO.sub.3       K H 7-CONH.sub.2 5-CH.sub.2 CH.sub.2SO.sub.3 K H C.sub.6       H.sub.4-p-OSO.sub.3 K 6 4-CH.sub.2 OC.sub.6 H.sub.5 H 7-CONHCH.sub.3      5-CH.sub.2 OC.sub.6 H.sub.5 H CH.sub.2 OPh 6 4-CH.sub.2 OOCC.sub.6      H.sub.5 H 7-CH.sub.2 Ph 5-CH.sub.2 OOCC.sub.6 H.sub.5 H CH.sub.2      SO.sub.2 NHPh 6 5-CH.sub.2 COOCH.sub.3 H 7-CH.sub.2 SO.sub.3       K 5-CH.sub.2 COOCH.sub.3 CH.sub.2 SO.sub.2 NHCH.sub.3 CH.sub.2 SO.sub.2      NHCH.sub.3 6 4-C.sub.6 H.sub.4-p-SO.sub.2 N(C.sub.2 H.sub.5).sub.2 H      7-CH.sub.2 OSO.sub.3 K 5-C.sub.6 H.sub.4-p-SO.sub.2 N(C.sub.2       H.sub.5).sub.2 H C.sub.6 H.sub.4-p-SO.sub.2 NHCH.sub.3 6 4-CH.sub.2      CH.sub.2 NHCOOCH.sub.3 H 7-C.sub.6 H.sub.4-p-SO.sub.3 K 5-CH.sub.2      CH.sub.2 NHCOOCH.sub.3 CH.sub.2 COOCH.sub.3 CH.sub.2 COOCH.sub.3 5,6      4-CH.sub.2 NHCONHCH.sub.3 H 7-CH.sub.2 CH.sub.2 OH 5-CH.sub.2       NHCONHCH.sub.3 H CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2 6 4-CH.sub.2      CONH.sub.2 H 7-CH.sub.2 Cl 5-CH.sub.2 CONH.sub.2 C.sub.2 H.sub.5 C.sub.6      H.sub.4-p-NHCOOCH.sub.3 6 5-CH.sub.2 CONHCH.sub.3 C.sub.4 H.sub.9n      7-C.sub.6 H.sub.4-p-Br 5-CONH.sub.2 C.sub.2 H.sub.5 CH.sub.2 CH.sub.2      CONH.sub.2 6 4-CH.sub.2 CON(CH.sub.3).sub.2 H H 3-SO.sub.2 NH.sub.2      C.sub.2 H.sub.5 C.sub.6 H.sub.4-p-CONHCH.sub.3 6 4-CH.sub.2 CH.sub.2      OCH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 H 4-COCH.sub.3 5-SO.sub.2 NHCH.sub.3      C.sub.2 H.sub.5 C.sub.6 H.sub.4-p-SCH.sub.3 6 4-CH.sub.2 SC.sub.2      H.sub.5 H 4-NO.sub.2 5-SO.sub.2 N(C.sub.2 H.sub.5).sub.2 CH.sub.2      CH.sub.2 SCH.sub.3 CH.sub. 2 CH.sub.2 SCH.sub.3 6 5-CH.sub.2 SC.sub.6      H.sub.5 H 4-Cl 5-SO.sub.3 C.sub.6 H.sub.5 H CH.sub.2C.sub.6       H.sub.4-p-SCH.sub.3 6 4-CH.sub.2 SO.sub.2 C.sub.2 H.sub.5 CH.sub.3 4-CN      5-SCH.sub.3 CH.sub.2 SO.sub.2 C.sub.2 H.sub.5 CH.sub.2 SO.sub.2 C.sub.2      H.sub.5 6 2,4-di-CH.sub.2 SO.sub.2 C.sub.6 H.sub.5 CH.sub.3 4-NHSO.sub.2      CH.sub.3 2,5-di-SCN H CH.sub.2 SO.sub.2 Ph 6 4-C.sub.6       H.sub.3-o,-p-di-CN CH.sub.3 7-CH.sub.3 5-SO.sub.2 C.sub.6 H.sub.5 H      CH.sub.2 CH.sub.2 OSO.sub.3 K 6 4-C.sub.6 H.sub.2-o,.sub.--m,-p-tri-Cl      CH.sub.3 7-OCH.sub.3 2-CHO5-CN H C.sub.6 H.sub.4-p-OSO.sub.3 K 6      2,6-di-OSO.sub.3 Na CH.sub.3 4-Ph 5-CONHC.sub.2       H.sub.5 H CH.sub.2(C.sub.8 H.sub.4 O.sub.2 N) 6 H H 7-CH.sub.2 (C.sub.4      H.sub.4 O.sub.2 N) 5-CON(C.sub.2 H.sub.5).sub.2 C.sub.2 H.sub.5 C.sub.2      H.sub. 5 6 H H 7-CH.sub.2 (C.sub.4 H.sub.3 O) 3-C.sub.6 H.sub.11 C.sub.2      H.sub.5 C.sub.2 H.sub.5 6 5-CH.sub.2 (C.sub.8 H.sub.4 O.sub.2 N) H H      3-SC.sub.6 H.sub.5 C.sub.2 H.sub.5 C.sub.2 H.sub.5 6 5-CH.sub.2 (C.sub.4      H.sub.3 O) H H 3-NHSO.sub.2 C.sub.6 H.sub.5 C.sub.2 H.sub.5 C.sub.2      H.sub.5

    TABLE 5       ##STR10##        Cinnamoyl         Group Position R.sub.1 on D R.sub.5 Substituents on      B R.sub.1 on C R.sub.3 R.sub.4 R.sub.8 R.sub.7        6 H H H H H H  H H 6 4-NO.sub.2 H 4-COCH.sub.3 7-CH.sub.3 CH.sub.3      CH.sub.3 CH.sub.3 Ph 6 4-CN H 4-NO.sub.2 7-COCH.sub.3 CH.sub.3 CH.sub.3      H C.sub.6 H.sub.11   6,7 5-COCH.sub.3 H 4-Cl 7-OCH.sub.3 CH.sub.3      CH.sub.3 H CH.sub.2CHCH.sub.2 7 4-COPh CH.sub.3 4-CN 7-SO.sub.3 Na      CH.sub.3 CH.sub.3 H CH.sub.2 OOC.sub.2 H.sub.5 5 2,4-di-COOH CH.sub.3      4-NHSO.sub.2 CH.sub.3 7-OCH.sub.2 CH.sub.2 SO.sub.4 K CH.sub.3 CH.sub.3      H C.sub.6 H.sub.4-p-OOCCH.sub.3 6 4-OOCCH.sub.3 CH.sub.3 7-CH.sub.3      5-OCH.sub.2 CH.sub.2 SO.sub.4 K CH.sub.3 CH.sub.3 H C.sub.6       H.sub.104-CH.sub.3 6 4-NHCOCH.sub.3 CH.sub.3 7-OCH.sub.3 7-CH.sub.3      CH.sub.3 H H CH.sub.2 CH.sub.2 (C.sub.4 H.sub.4 O.sub.2 N) 6 4-NHCOPh      CH.sub.3 4-Ph 7-Ph CH.sub.3 H H CH.sub.2 CH.sub.2 NO.sub.2 4 4-C.sub.2      H.sub.5 CH.sub.3 H 7-NO.sub.2 CH.sub.3 H H C.sub.6 H.sub.4-p-NO.sub.2 6      4-Ph H H 7-OCH.sub.3 CH.sub.3 H H CH.sub. 2 NHOCCH.sub.3 6 2,5-di-Cl H      4-SO.sub.3 Na 7-NHCOCH.sub.3 CH.sub.3 H H CH.sub.2 NHSO.sub.2 CH.sub.3 6      2-Cl4-SO.sub.2 CH.sub.3 H 4-SO.sub.3 Na 7-NHSO.sub.2 CH.sub.3 CH.sub.3 H      H C.sub.6 H.sub.4-p-NHOCCH.sub.3 6 4-NHSO.sub.2 CH.sub.3 H 7-OCH.sub.2      CH.sub.2 SO.sub.4 K 7-COOCH.sub.3 CH.sub.3 C.sub.2 H.sub.5 C.sub.2      H.sub.5 C.sub.6 H.sub.4-p-NHSO.sub.2       CH.sub.3 6 4-COOCH.sub.3 H 7-OCH.sub.2 CH.sub.2 SO.sub.4 K 7-COOH H H H      C.sub.6 H.sub.104-NHOCCH.sub.3 6 2-OCH.sub.3 C.sub.2 H.sub.5 4-NHCOPh      7-Cl CH.sub.3 CH.sub.3 CH.sub.3 CH.sub.2 CH.sub.2 Cl 5 4-OC.sub.2      H.sub.5 C.sub.2 H.sub.5 4-NHCOPh 5,7-di-Br CH.sub.3 CH.sub.3 H C.sub.6      H.sub.4-p-Br 6 4-SO.sub.3 Na C.sub.2 H.sub.5 7-NHCOCH.sub.3 5,7-di-Br      CH.sub.3 CH.sub.3 H C.sub.6 H.sub.4-p-CN 6 2-SO.sub.3 Na C.sub.2 H.sub.5      7-OOCC.sub.2 H.sub.5 5-OCH.sub.37-NHCOCH.sub.3 CH.sub.3 CH.sub.3 H      CH.sub.2 CH.sub.2 CN 7 2-OCH.sub.34-SO.sub.3 K H 4-COOH 7-CH.sub.2      OOCCH.sub.3 CH.sub.3 CH.sub.3 H CH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 6      4-OCH.sub.2 CH.sub.2 OSO.sub.3 K H H 7-CH.sub.2 Cl CH.sub.3 CH.sub.3 H      CH.sub.2 CH.sub.2 OCH.sub.2 CH.sub.2 OC.sub.2 H.sub.5   6,7 2-SO.sub.3   5      Na-Cl H H 7-CN CH.sub.3 H H CH.sub.2 Ph 6 4-Cl H 7-SO.sub.2 CH.sub.3      7-OOCCH.sub.3 CH.sub.3 H H CH.sub.2 C.sub.6 H.sub.11 6 4-OH H 7-CF.sub.3      7-COOH CH.sub.3 H H C.sub.6 H.sub.4-o-OH 6 4-CH.sub.2 OOCCH.sub.3      C.sub.3 H.sub.7n 7-COOCH.sub.3 7-OH CH.sub.3 H H CH.sub.2 CH.sub.2 OH 6      4-SO.sub.3 K C.sub.3 H.sub.7n 7-CHO 7-CH.sub.2 CHCH.sub.2 CH.sub.3 H H      CH.sub.2 CH.sub.2SO.sub.3 K 6 4-OPh H 7-CONH.sub.2 7-CH.sub.3 CH.sub.3 H      H C.sub.6 H.sub.4-p-OSO.sub.3       K 6 4-NO.sub.2 H 7-CONHCH.sub.3 7-COCH.sub.3 CH.sub.3 C.sub.2 H.sub.5      C.sub.2 H.sub.5 CH.sub. 2 OPh 6 5-CN H 7-CH.sub.2 Ph 7-OCH.sub.3 H H H      CH.sub.2 SO.sub.2 NHPh 6 4-COCH.sub.3 H 7-CH.sub.2 SO.sub.3 K 7-SO.sub.3      Na CH.sub.3 CH.sub.3 CH.sub.3 CH.sub.2 SO.sub.2 NHCH.sub.3 6 5-CH.sub.3      H 7-CH.sub.2 OSO.sub.3 K 7-OCH.sub.2 CH.sub.2 SO.sub.4 K CH.sub.3      CH.sub.3 H C.sub.6 H.sub.4-p-SO.sub.2 NHCH.sub.3 6 5-Ph H 7-C.sub.6      H.sub.4-p-SO.sub.3 K 7-OCH.sub.2 CH.sub.2 SO.sub.3 K CH.sub.3 CH.sub.3 H      CH.sub.2 COOCH.sub.3 6 5-OCH.sub.3 H 7-CH.sub.2 CH.sub.2 OH 7-CH.sub.3      CH.sub.3 CH.sub.3 H CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2 6 4,5-di-Br H      7-CH.sub.2 Cl 7-Ph CH.sub.3 CH.sub.3 H C.sub.6 H.sub.4-p-NHCOOCH.sub.3 6      5-COOH C.sub.4 H.sub.9n 7-C.sub.6 H.sub.4-p-Br 7-NO.sub.2 H H H CH.sub.2      CH.sub.2 CONH.sub.2 6 H H H 7-OCH.sub.3 CH.sub.3 CH.sub.3 CH.sub.3      C.sub.6       H.sub.4-p-CONHCH.sub.3 6 4-NO.sub.2 H 4-COCH.sub.3 7-NHCOCH.sub.3      CH.sub.3 CH.sub.3 H C.sub.6 H.sub.4-p-SCH.sub.3 6 4-CN H 4-NO.sub.2      7-NHSO.sub.2 CH.sub.3 CH.sub.3 CH.sub.3 H CH.sub.2 CH.sub.2 SCH.sub.3 6      5-COCH.sub.3 H 4-Cl 7-COOCH.sub.3 CH.sub.3 CH.sub.3 H CH.sub.2C.sub.6      H.sub.4-p-SCH.sub.3 6 4-COPh CH.sub.3 4-CN 7-COOH CH.sub.3 CH.sub.3 H      CH.sub.2 SO.sub.2 C.sub.2 H.sub.5 6 2,4-di-COOH CH.sub.3 4-NHSO.sub.2      CH.sub.3 7-Cl CH.sub.3 CH.sub.3 H CH.sub.2 SO.sub.2 Ph 6 4-OOCCH.sub.3      CH.sub.3 7-CH.sub.3 7,8-di-Br CH.sub.3 H H CH.sub.2 CH.sub.2 OSO.sub.3 K      6 4-NHCOCH.sub.3 CH.sub.3 7-OCH.sub.3 7,8-di-Br CH.sub.3 H H C.sub.6      H.sub.4-p-OSO.sub.3 K 6 4-NHCOPh CH.sub.3 4-Ph 7-OCH.sub.38-NHCOCH.sub.3      CH.sub.3 H H CH.sub.2 (C.sub.8 H.sub.4 O.sub.2 N) 5 4-CH.sub.2       CHCH.sub.2 H H 7-NHCOCH.sub.3 C.sub.2 H.sub.5 H H C.sub.2 H.sub.5   5,6      H CH.sub.3 H 7-OCPh C.sub.2 H.sub.5 H H C.sub.2 H.sub.5 6 4-CONH.sub.2 H      H 7-CH.sub.2 CONHCH.sub.3 H H H H 6 3-SO.sub.2 NH.sub.2 H 4-COCH.sub.3      7-CH.sub.2       CON(CH.sub.3).sub.2 CH.sub.3 CH.sub.3 CH.sub.3 Ph 6 4-SO.sub.2       NHCH.sub.3 H 4-NO.sub.2 7-CH.sub.2 CH.sub.2 OCH.sub.2 CH.sub.2 OC.sub.2      H.sub.5 CH.sub.3 CH.sub.3 H C.sub.6 H.sub.11 6 4-SO.sub.2 N(C.sub.2      H.sub.5).sub.2 H 4-Cl 7-CH.sub.2 SC.sub.2 H.sub.5 CH.sub.3 CH.sub.3 H      CH.sub.2CHCH.sub.2   6,7 4-SO.sub.3 C.sub.6 H.sub.5 CH.sub.3 4-CN      7-CH.sub.2 SC.sub.6 H.sub.5 CH.sub.3 CH.sub.3 H CH.sub.2 OOCC.sub.2      H.sub.5 5 4-SCH.sub.3 CH.sub.3 4-NHSO.sub.2 CH.sub.3 7-CH.sub.2 SO.sub.2      C.sub.2 H.sub.5 CH.sub.3 CH.sub.3 H C.sub.6 H.sub.4-p-OOCCH.sub.3 6      2,4-di-SCN CH.sub.3 7-CH.sub.3 7-CH.sub.2 SO.sub.2 C.sub.6 H.sub.5      CH.sub.3 CH.sub.3 H C.sub.6 H.sub.104-CH.sub.3 6 4-SO.sub.2 C.sub.6      H.sub.5 CH.sub.3 7-OCH.sub.3 7-C.sub.6 H.sub.3-o, -p-di-CN CH.sub.3 H H      CH.sub.2 CH.sub.2(C.sub.4 H.sub.4 O.sub.2 N) 6 2-CHO4-CN CH.sub.3 4-Ph      7-C.sub.6 H.sub.2-o,.sub.--m,-p-tri-Cl CH.sub.3 H H CH.sub.2 CH.sub.2      NO.sub.2 4 4-CONHC.sub.2 H.sub.5 CH.sub.3 H 5,7-di-OSO.sub.3       NH(CH.sub.3).sub.3 CH.sub.3 H H C.sub.6       H.sub.4-p-NO.sub.2 6 4-CON(C.sub.2 H.sub.5).sub.2 H H 5,7-di-OSO.sub.3      Na CH.sub.3 H H CH.sub.2 NHOCCH.sub.3 6 3-C.sub.6 H.sub.11 H 4-SO.sub.3      Na 5-OSO.sub.3 N(CH.sub.3).sub.3 CH.sub.3 H H CH.sub.2 NHSO.sub.2      CH.sub.3 6 3-SC.sub.6 H.sub.5 H 4-SO.sub.3 Na 7-SO.sub.3       NH(CH.sub.3).sub.3 CH.sub.3 H H C.sub.6 H.sub.4-p-NHOCCH.sub.3 6      4-NHSO.sub.2 C.sub.6 H.sub.5 H 7-OCH.sub.2 CH.sub.2 SO.sub.4       K 5,7-di-OSO.sub.3 Na CH.sub.3 C.sub.2 H.sub.5 C.sub.2 H.sub.5 C.sub.6      H.sub.4-p-NHSO.sub.2 CH.sub.3 6 4-SC.sub.6 H.sub.11 H 7-OCH.sub.2      CH.sub.2 SO.sub.4 K 7-SC.sub.6 H.sub.11 H H H C.sub.6       H.sub.104-NHOCCH.sub.3 6 4-C.sub.6 H.sub.4-p-CH.sub.3 C.sub.2 H.sub.5      4-NHCOPh 7-C.sub.6 H.sub.4-p-CH.sub.3 CH.sub.3 CH.sub.3 CH.sub.3      CH.sub.2 CH.sub.2 Cl 5 4-C.sub.6 H.sub.4-p-CH.sub.2 CHCH.sub.2 C.sub.2      H.sub.5 4-NHCOPh 7-C.sub.6 H.sub.4-p-CH.sub.2 CHCH.sub.2 CH.sub.3      CH.sub.3 H C.sub.6 H.sub.4-p-Br 6 4-OCH.sub.2 CH.sub.2 NO.sub.2 C.sub.2      H.sub.5 7-NHCOCH.sub.3 7-OCH.sub.2 CH.sub.2 NO.sub.2 CH.sub.3 CH.sub.3 H      C.sub.6 H.sub.4-p-CN 6 2-CH.sub.2 NHCOCH.sub.3 C.sub.2       H.sub.5 7-OOCC.sub.2 H.sub.5 7-CH.sub.2 NHCOCH.sub.3 CH.sub.3 CH.sub.3      H CH.sub.2 CH.sub.2 CN 7 4-CH.sub.2 NHSO.sub.2 C.sub.2 H.sub.5 H 4-COOH      7-CH.sub.2 NHSO.sub.2 C.sub.2 H.sub.5 CH.sub.3 CH.sub.3 H CH.sub.2      CH.sub.2 OC.sub.2 H.sub.5 6 4-CH.sub.2 CH.sub.2 Cl H H 7-CH.sub.2      CH.sub.2 Cl CH.sub.3 CH.sub.3 H CH.sub.2 CH.sub.2 OCH.sub.2 CH.sub.2      OC.sub.2 H.sub.5   6,7 2,6-di-CH.sub.2 CN H H 5,7-di-CH.sub.2 CN      CH.sub.3 H H CH.sub.2 Ph 6 4-CH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 H      7-SO.sub.2 CH.sub.3 7-CH.sub.2 CH.sub.2 OC.sub.2 H.sub.5 CH.sub.3 H H      CH.sub.2 C.sub.6 H.sub.11 6 4-CH.sub.2C.sub.6 H.sub.5 H 4-CH.sub.2      C.sub.6 H.sub.5 7-COOH CH.sub.3 H H C.sub.6 H.sub.4-o-OH 6 4-CH.sub.2      C.sub.6 H.sub.11 C.sub.3 H.sub.7n 7-COOCH.sub.3 7-CH.sub.2 C.sub.6      H.sub.11 CH.sub.3 H H CH.sub.2 CH.sub.2 OH 6 4-CH.sub.2 CH(OH)CH.sub.2      OH C.sub.3 H.sub.7n 7-CHO 7-CH.sub.2 CH(OH)CH.sub.2 OH CH.sub.3 H H      CH.sub.2 CH.sub.2SO.sub.3 K 6 4-CH.sub.2 CH.sub.2SO.sub.3       K H 7-CONH.sub.2 7-CH.sub.2 CH.sub.2SO.sub.3 K CH.sub.3 H H C.sub.6      H.sub.4-p-OSO.sub.3 K 6 4-CH.sub.2 OC.sub.6 H.sub.5 H 7-CONHCH.sub. 3      7-CH.sub.2 OC.sub.6 H.sub.5 CH.sub.3 C.sub.2 H.sub.5 C.sub.2 H.sub.5      CH.sub.2 OPh 6 4-CH.sub.2 OOCC.sub.6 H.sub.5 H 7-CH.sub.2 Ph 7-CH.sub.2      OOCC.sub.6 H.sub.5 H H H CH.sub.2 SO.sub.2 NHPh 6 5-CH.sub.2 COOCH.sub.3      H 7-CH.sub.2 SO.sub.3 K 7-CH.sub.2 COOCH.sub.3 CH.sub.3 CH.sub.3      CH.sub.3 CH.sub.2 SO.sub.2 NHCH.sub.3 6 4-C.sub.6 H.sub.4-p-SO.sub.2      N(C.sub.2 H.sub.5).sub.2 H 7-CH.sub.2 OSO.sub.3 K 7-C.sub.6       H.sub.4-p-SO.sub.2 N(C.sub.2 H.sub.5).sub.2 CH.sub.3 CH.sub.3 H C.sub.6      H.sub.4-p-SO.sub.2 NHCH.sub.3 6 4-CH.sub.2 CH.sub.2 NHCOOCH.sub.3 H      7-C.sub.6 H.sub.4-p-SO.sub.3 K 7-CH.sub.2 CH.sub.2 NHCOOCH.sub.3      CH.sub.3 CH.sub.3 H CH.sub.2 COOCH.sub.3 6 4-CH.sub.2 NHCONHCH.sub.3 H      7-CH.sub.2 CH.sub.2 OH 7-CH.sub.2 NHCONHCH.sub.3 CH.sub.3 CH.sub.3 H      CH.sub.2 SO.sub.2 N(CH.sub.3).sub.2 6 4-CH.sub.2 CONH.sub.2 H 7-CH.sub.2      Cl 7-CH.sub. 2 CONH.sub.2 CH.sub.3 CH.sub.3 H C.sub.6       H.sub.4-p-NHCOOCH.sub.3 6 5-CH.sub.2 CONHCH.sub.3 C.sub.4 H.sub.9n      7-C.sub.6 H.sub.4-p-Br 7-CONH.sub.2 H H H CH.sub.2 CH.sub.2 CONH.sub.2 6      4-CH.sub.2 CON(CH.sub.3).sub.2 H H 7-SO.sub.2 NH.sub.2 CH.sub.3 CH.sub.3      CH.sub.3 C.sub.6 H.sub.4-p-CONHCH.sub.3 6 4-CH.sub.2 CH.sub.2 OCH.sub.2      CH.sub.2 OC.sub.2 H.sub.5 H 4-COCH.sub.3 7-SO.sub.2 NHCH.sub.3 CH.sub.3      CH.sub.3 H C.sub.6 H.sub.4-p-SCH.sub.3 6 4-CH.sub.2 SC.sub.2 H.sub.5 H      4-NO.sub.2 7-SO.sub.2 N(C.sub.2 H.sub.5).sub.2 CH.sub.3 CH.sub.3 H      CH.sub.2 CH.sub.2 SCH.sub.3 6 5-CH.sub.2 SC.sub.6 H.sub.5 H 4-Cl      7-SO.sub.3 C.sub.6 H.sub.5 CH.sub.3 CH.sub.3 H CH.sub.2C.sub.6       H.sub.4-p-SCH.sub.3   6,7 4-di-CH.sub.2 SO.sub.2 C.sub.6 H.sub.5      CH.sub.3 4-CN 7-SCH.sub.3 CH.sub.3 CH.sub.3 H CH.sub.2 SO.sub.2 C.sub.2      H.sub.5 6 2,4-CH.sub.2 SO.sub.2 C.sub.6 H.sub.5 CH.sub.3 4-NHSO.sub.2      CH.sub.3 5,7-di-SCH CH.sub.3 CH.sub.3 H CH.sub.2 SO.sub.2 Ph 6 4-C.sub.6      H.sub.3-o,-p-di-CN CH.sub.3 7-CH.sub.3 7-SO.sub.2 C.sub.6 H.sub.5      CH.sub.3 H H CH.sub.2 CH.sub.2 OSO.sub.3 K 6 4-C.sub.6       H.sub.2-o,.sub.--m,-p-tri-Cl CH.sub.3 7-OCH.sub.3 5-CHO7-CN CH.sub.3 H      H C.sub.6 H.sub.4-p-OSO.sub.3 K 6 2,6-di-OSO.sub.3 Na CH.sub.3 4-Ph      7-CONHC.sub.2 H.sub.5 CH.sub.3 H H CH.sub.2 (C.sub.8 H.sub.4 O.sub.2 N)      6 H H 7-CH.sub.2 (C.sub.4 H.sub.4 O.sub.2 N) 7-CON(C.sub.2       H.sub.5).sub.2 CH.sub.3 H H C.sub.2 H.sub.5 6 H H 7-CH.sub.2 (C.sub.4      H.sub.3 O) 7-C.sub.6 H.sub.11 CH.sub.3 H H C.sub.2 H.sub.5 6 5-CH.sub.2      (C.sub.8 H.sub.4 O.sub.2 N) H H 7-SC.sub.6 H.sub.5 CH.sub.3 H H C.sub.2      H.sub.5 6 5-CH.sub.2 (C.sub.4 H.sub.3 O) H H 7-NHSO.sub.2 C.sub.6      H.sub.5 CH.sub.3 C.sub.2 H.sub.5 C.sub.2 H.sub.5 C.sub.2       H.sub.5

                                      TABLE 6                                      __________________________________________________________________________      ##STR11##                                                                     Cinna-                                                                         moyl                                                                           Group                                                                          Posi-                 Substituents                                             tion                                                                               R.sub.1 on D R.sub.5                                                                             on B     R.sub.1 on C  R.sub.3                                                                             R.sub.7                      __________________________________________________________________________     6  H             H    H        H             H    H                            6  4-NO.sub.2    H    4-COCH.sub.3                                                                            6-CH.sub.3    CH.sub.3                                                                            Ph                           6  4-CN          H    4-NO.sub.2                                                                              6-COCH.sub.3  C.sub.2 H.sub.5                                                                     C.sub.6 H.sub.11             6  5-COCH.sub.3  H    4-Cl     6-OCH.sub.3   H    CH.sub.2CHCH.sub.2           7  4-COPh        CH.sub.3                                                                            4-CN     6-SO.sub.3 Na H    CH.sub.2 OOCC.sub.2                                                            H.sub.5                      5  2,4-di-COOH   CH.sub.3                                                                            4-NHSO.sub.2 CH.sub.3                                                                   6-OCH.sub.2 CH.sub.2 SO.sub.4 K                                                              H    C.sub.6 H.sub.4                                                                -p-OOCCH.sub.3               6  4-OOCCH.sub.3 CH.sub.3                                                                            7-CH.sub.3                                                                              6-OCH.sub.2 CH.sub.2 SO.sub.4 K                                                              H    C.sub.6 H.sub.104-CH.sub                                                       .3                           6  4-NHCOCH.sub.3                                                                               CH.sub.3                                                                            7-OCH.sub.3                                                                             6-CH.sub.3    H    CH.sub.2 CH.sub.2                                                              (C.sub.4 H.sub.4                                                               O.sub.2 N)                   6  4-NHCOPh      CH.sub.3                                                                            4-Ph     6-Ph          CH.sub.3                                                                            CH.sub.2 CH.sub.2                                                              NO.sub.2                     4,6                                                                               4-C.sub.2 H.sub.5                                                                            CH.sub.3                                                                            H        6-NO.sub.2    CH.sub.3                                                                            C.sub.6 H.sub.4                                                                -p-NO.sub.2                  6  4-Ph          H    H        6-OCH.sub.3   CH.sub.3                                                                            CH.sub.2 NHOCCH.sub.3        6  2,5-Cl        H    4-SO.sub.3 Na                                                                           6-NHCOCH.sub.3                                                                               C.sub.2 H.sub.5                                                                     CH.sub.2 NHSO.sub.2                                                            CH.sub.3                     6  2-Cl4-SO.sub.2 CH.sub.3                                                                      H    4-SO.sub.3 Na                                                                           6-NHSO.sub.2 CH.sub.3                                                                        CH.sub.3                                                                            C.sub.6 H.sub.4                                                                -p-NHOCCH.sub.3              6  4-NHSO.sub. 2 CH.sub.3                                                                       H    7-OCH.sub.2 CH.sub.2 SO.sub.4 K                                                         6-COOCH.sub.3 CH.sub.3                                                                            C.sub.6 H.sub.4                                                                -p-NHSO.sub.2 CH.sub.3       6  4-COOCH.sub.3 H    7-OCH.sub.2 CH.sub.2 SO.sub.4 K                                                         6-COOH        H    C.sub.6 H.sub.104-NHOCCH                                                       .sub.3                       6  2-OCH.sub.3   C.sub.2 H.sub.5                                                                     4-NHCOPh 6-Cl          CH.sub.3                                                                            CH.sub.2 CH.sub.2 Cl         5  4-OC.sub.2 H.sub.5                                                                           C.sub.2 H.sub.5                                                                     4-NHCOPh 6,8-di-Br     C.sub.2 H.sub.5                                                                     C.sub.6 H.sub.4 -p-Br        6  4-SO.sub.3 Na C.sub.2 H.sub.5                                                                     7-NHCOCH.sub.3                                                                          6,8-di-Br     H    C.sub.6 H.sub.4 -p-CN        6  2-SO.sub.3 Na C.sub.2 H.sub.5                                                                     7-OOCC.sub.2 H.sub.5                                                                    6-OCH.sub.38-NHCOCH.sub.3                                                                    H    CH.sub.2 CH.sub.2 CN         7  2-OCH.sub.34-SO.sub.3 K                                                                      H    4-COOH   6-CH.sub.2 OOCCH.sub.3                                                                       H    CH.sub.2 CH.sub.2                                                              OC.sub.2 H.sub.5             6  4-OCH.sub.2 CH.sub.2 OSO.sub.3 K                                                             H    H        6-CH.sub.2 Cl H    CH.sub.2 CH.sub.2                                                              OCH.sub.2 CH.sub.2                                                             OC.sub.2 H.sub.5             6  2-SO.sub.3 Na5-Cl                                                                            H    H        6-CN          H    CH.sub.2 Ph                  6  4-Cl          H    7-SO.sub.2 CH.sub.3                                                                     6-OOCCH.sub.3 CH.sub.3                                                                            CH.sub. 2 C.sub.6                                                              H.sub.11                     6  4-OH          H    7-CF.sub.3                                                                              6-COOH        CH.sub.3                                                                            C.sub.6 H.sub.4 -o-OH        6  4-CH.sub.2 OOCCH.sub.3                                                                       C.sub.3 H.sub.7n                                                                    7-COOCH.sub.3                                                                           6-OH          CH.sub.3                                                                            CH.sub.2 CH.sub.2 OH         5,6                                                                               4-SO.sub.3 K  C.sub.3 H.sub.7n                                                                    7-CHO    6-CH.sub.2 CHCH.sub.2                                                                        C.sub.2 H.sub.5                                                                     CH.sub.2 CH.sub.2SO.sub.                                                       3 K                          6  4-OPh         H    7-CONH.sub.2                                                                            6-CH.sub.3    CH.sub.3                                                                            C.sub.6 H.sub.4                                                                -p-OSO.sub.3 K               6  4-NO.sub.2    H    7-CONHCH.sub.3                                                                          6-COCH.sub.3  CH.sub.3                                                                            CH.sub.2 OPh                 6  5-CN          H    7-CH.sub.2 Ph                                                                           6-OCH.sub.3   H    CH.sub.2 SO.sub.2 NHPh       6  4-COCH.sub.3  H    7-CH.sub.2 SO.sub.3 K                                                                   6-SO.sub.3 Na CH.sub.3                                                                            CH.sub.2 SO.sub.2                                                              NHCH.sub.3                   6  5-CH.sub.3    H    7-CH.sub.2 OSO.sub.3 K                                                                  6-OCH.sub.2 CH.sub.2 SO.sub.4 K                                                              H    C.sub.6 H.sub.4                                                                -p-SO.sub.2 NHCH.sub.3       6  5-Ph          H    7-C.sub.6 H.sub.4 -p-SO.sub.3 K                                                         6-OCH.sub.2 CH.sub.2 SO.sub.3 K                                                              H    CH.sub.2 COOCH.sub.3         6  5-OCH.sub.3   H    7-CH.sub.2 CH.sub.2 OH                                                                  6-CH.sub.3    H    CH.sub.2 SO.sub.2                                                              N(CH.sub.3).sub.2            6  4,5-di-Br     H    7-CH.sub.2 Cl                                                                           6-Ph          H    C.sub.6 H.sub.4                                                                -p-NHCOOCH.sub.3             6  5-COOH        C.sub.4 H.sub.9n                                                                    7-C.sub.6 H.sub.4 -p-Br                                                                 6-NO.sub.2    C.sub.2 H.sub.5                                                                     CH.sub.2 CH.sub.2                                                              CONH.sub.2                   6  H             H    H        6-OCH.sub.3   C.sub.2 H.sub.5                                                                     C.sub.6 H.sub.4                                                                -p-CONHCH.sub.3              6  4-NO.sub.2    H    4-COCH.sub.3                                                                            6-NHCOCH.sub.3                                                                               CH.sub.3                                                                            C.sub.6 H.sub.4                                                                -p-SCH.sub.3                 6  4-CN          H    4-NO.sub.2                                                                              6-NHSO.sub.2 CH.sub.3                                                                        C.sub.3 H.sub.7n                                                                    CH.sub.2 CH.sub.2                                                              SCH.sub.3                    6  5-COCH.sub.3  H    4-Cl     6-COOCH.sub.3 H    CH.sub.2C.sub.6 H.sub.4                                                        -p-SCH.sub.3                 6  4-COPh        CH.sub.3                                                                            4-CN     6-COOH        CH.sub.3                                                                            CH.sub.2 SO.sub.2                                                              C.sub.2 H.sub.5              6  2,4-di-COOH   CH.sub.3                                                                            4-NHSO.sub.2 CH.sub.3                                                                   6-Cl          H    CH.sub.2 SO.sub.2 Ph         6  4-OOCCH.sub.3 CH.sub.3                                                                            7-CH.sub.3                                                                              5,6-di-Br     H    CH.sub.2 CH.sub.2                                                              OSO.sub.3 K                  6  4-NHCOCH.sub.3                                                                               CH.sub.3                                                                            7-OCH.sub.3                                                                             6,8-di-Br     H    C.sub.6 H.sub.4                                                                -p-OSO.sub. 3 K              6  4-NHCOPh      CH.sub.3                                                                            4-Ph     6-OCH.sub.38-NHCOCH.sub.3                                                                    H    CH.sub.2 (C.sub.8                                                              H.sub.4 O.sub.2 N)           5  4-CH.sub.2 CHCH.sub.2                                                                        H    H        6-NHCOCH.sub.3                                                                               C.sub.2 H.sub.5                                                                     C.sub.2 H.sub.5              6,7                                                                               H             CH.sub.3                                                                            H        6-OCPh        C.sub.2 H.sub.5                                                                     C.sub.2 H.sub.5              6  4-CONH.sub.2  H    H        6-CH.sub.2 CONHCH.sub.3                                                                      H    H                            6  3-SO.sub.2 NH.sub.2                                                                          H    4-COCH.sub.3                                                                            6-CH.sub.2 CON(CH.sub.3).sub.2                                                               CH.sub.3                                                                            Ph                           6  4-SO.sub.2 NHCH.sub.3                                                                        H    4-NO.sub.2                                                                              6-CH.sub.2 CH.sub.2 OCH.sub.2 CH.sub.2                                         OC.sub.2 H.sub.5                                                                             C.sub.2 H.sub.5                                                                     C.sub.6 H.sub.11             6  4-SO.sub.2 N(C.sub.2 H.sub.5).sub.2                                                          H    4-Cl     6-CH.sub.2 SC.sub.2 H.sub.5                                                                  H    CH.sub.2CHCH.sub.2           7  4-SO.sub.3 C.sub.6 H.sub.5                                                                   CH.sub.3                                                                            4-CN     6-CH.sub.2 SC.sub.6 H.sub.5                                                                  H    CH.sub.2 OOCC.sub.2                                                            H.sub.5                      5  4-SCH.sub.3   CH.sub.3                                                                            4-NHSO.sub.2 CH.sub.3                                                                   6-CH.sub.2 SO.sub.2 C.sub.2 H.sub.5                                                          H    C.sub.6 H.sub.4                                                                -p-OOCCH.sub.3               6  2,4-di-SCN    CH.sub.3                                                                            7-CH.sub.3                                                                              6-CH.sub.2 SO.sub.2 C.sub.6 H.sub.5                                                          H    C.sub.6                                                                        H.sub.104-CH.sub.3           6  4-SO.sub.2 C.sub.6 H.sub.5                                                                   CH.sub.3                                                                            7-OCH.sub.3                                                                             6-C.sub.6 H.sub.3 -o, -p-di-CN                                                               H    CH.sub.2 CH.sub.2(C.sub.                                                       4 H.sub.4 O.sub.2 N)         6  2-CHO4-CN     CH.sub.3                                                                            4-Ph     6-C.sub.6 H.sub.2 -o, .sub.--m, -p-tri-Cl                                                    CH.sub.3                                                                            CH.sub.2 CH.sub.2                                                              NO.sub.2                     4  4-CONHC.sub.2 H.sub.5                                                                        CH.sub.3                                                                            H        5,6-di-OSO.sub.3 NH(CH.sub.3).sub.3                                                          CH.sub.3                                                                            C.sub.6 H.sub.4                                                                -p-NO.sub.2                  6  4-CON(C.sub.2 H.sub.5).sub.2                                                                 H    H        5,6-di-SO.sub.3 NH(CH.sub.3).sub.3                                                           CH.sub.3                                                                            CH.sub.2 NHOCCH.sub.3        6  3-C.sub.6 H.sub.11                                                                           H    4-SO.sub.3 Na                                                                           6-OSO.sub.3 NH(CH.sub.3).sub.3                                                               C.sub.2 H.sub.5                                                                     CH.sub.2 NHSO.sub.2                                                            CH.sub.3                     6  3-SC.sub.6 H.sub.5                                                                           H    4-SO.sub.3 Na                                                                           6,8-di-OSO.sub.3 Na                                                                          CH.sub.3                                                                            C.sub.6 H.sub.4                                                                -p-NHOCCH.sub.3              6  4-NHSO.sub.2 C.sub.6 H.sub.5                                                                 H    7-OCH.sub.2 CH.sub.2 SO.sub.4 K                                                         6-SO.sub.3 NH(CH.sub.3).sub.3                                                                CH.sub.3                                                                            C.sub.6 H.sub.4                                                                -p-NHSO.sub.2 CH.sub.3       6  4-SC.sub.6 H.sub.11                                                                          H    7-OCH.sub.2 CH.sub.2 SO.sub.4 K                                                         6-SC.sub.6 H.sub.11                                                                          H    C.sub.6 H.sub.104-NHOCCH                                                       .sub.3                       6  4-C.sub.6 H.sub.4 -p-CH.sub.3                                                                C.sub.2 H.sub.5                                                                     4-NHCOPh 6-C.sub.6 H.sub.4 -p-CH.sub.3                                                                CH.sub.3                                                                            CH.sub.2 CH.sub.2 Cl         5  4-C.sub.6 H.sub.4 -p-CH.sub.2 CHCH.sub.2                                                     C.sub.2 H.sub.5                                                                     4-NHCOPh 6-C.sub.6 H.sub.4 -p-CH.sub.2 CHCH.sub.2                                                     C.sub.2 H.sub.5                                                                     C.sub.6 H.sub.4 -p-Br        6  4-OCH.sub.2 CH.sub.2 NO.sub.2                                                                C.sub.2 H.sub.5                                                                     7-NHCOCH.sub.3                                                                          6-OCH.sub.2 CH.sub.2 NO.sub.2                                                                H    C.sub.6 H.sub.4 -p-CN        6  2-CH.sub.2 NHCOCH.sub.3                                                                      C.sub.2 H.sub.5                                                                     7-OOCC.sub.2 H.sub.5                                                                    6-CH.sub.2 NHCOCH.sub.3                                                                      H    CH.sub.2 CH.sub.2 CN         7  4-CH.sub.2 NHSO.sub.2 C.sub.2 H.sub.5                                                        H    4-COOH   6-CH.sub.2 NHSO.sub.2 C.sub.2 H.sub.5                                                        H    CH.sub.2 CH.sub.2                                                              OC.sub.2 H.sub.5             6  4-CH.sub.2 CH.sub.2 Cl                                                                       H    H        6-CH.sub.2 CH.sub.2 Cl                                                                       H    CH.sub.2 CH.sub.2                                                              OCH.sub.2 CH.sub.2                                                             OC.sub.2 H.sub.5             6,7                                                                               2,6-di-CH.sub.2 CN                                                                           H    H        6,8-di-CH.sub.2 CN                                                                           H    CH.sub.2 Ph                  6  4-CH.sub.2 CH.sub.2 OC.sub.2 H.sub.5                                                         H    7-SO.sub.2 CH.sub.3                                                                     6-CH.sub.2 CH.sub.2 OC.sub.2 H.sub.5                                                         CH.sub.3                                                                            CH.sub.2 C.sub.6                                                               H.sub.11                     6  4-CH.sub.2 C.sub.6 H.sub.5                                                                   H    4-CH.sub.2 C.sub.6 H.sub.5                                                              6-COOH        CH.sub.3                                                                            C.sub.6 H.sub.4 -o-OH        6  4-CH.sub.2 C.sub.6 H.sub.11                                                                  C.sub.3 H.sub.7n                                                                    7-COOCH.sub.3                                                                           6-CH.sub.2 C.sub.6 H.sub.11                                                                  CH.sub.3                                                                            CH.sub.2 CH.sub.2 OH         6  4-CH.sub.2 CH(OH)CH.sub.2 OH                                                                 C.sub.3 H.sub.7n                                                                    7-CHO    6-CH.sub.2 CH(OH)CH.sub.2 OH                                                                 C.sub.2 H.sub.5                                                                     CH.sub.2 CH.sub.2SO.sub.                                                       3 K                          6  4-CH.sub.2 CH.sub.2SO.sub.3 K                                                                H    7-CONH.sub.2                                                                            6-CH.sub.2 CH.sub.2SO.sub.3 K                                                                CH.sub.3                                                                            C.sub.6 H.sub.4                                                                -p-OSO.sub.3 K               6  4-CH.sub.2 OC.sub.6 H.sub.5                                                                  H    7-CONHCH.sub.3                                                                          6-CH.sub.2 OC.sub.6 H.sub.5                                                                  CH.sub.3                                                                            CH.sub.2 OPh                 6  4-CH.sub.2 OOCC.sub.6 H.sub.5                                                                H    7-CH.sub.2 Ph                                                                           6-CH.sub.2 OOCC.sub. 6 H.sub.11                                                              H    CH.sub.2 SO.sub.2 NHPh       6  5-CH.sub.2 COOCH.sub.3                                                                       H    7-CH.sub.2 SO.sub.3 K                                                                   6-CH.sub.2 COOCH.sub.3                                                                       CH.sub.3                                                                            CH.sub.2 SO.sub.2                                                              NHCH.sub.3                   6  4-C.sub.6 H.sub.4 -p-SO.sub.2 N(C.sub.2 H.sub.5).sub.2                                       H    7-CH.sub.2 OSO.sub.3 K                                                                  6-C.sub.6 H.sub.4 -p-SO.sub.2 N(C.sub.2                                        H.sub.5).sub.2                                                                               H    C.sub.6 H.sub.4                                                                -p-SO.sub.2 NHCH.sub.3       6  4-CH.sub.2 CH.sub.2 NHCOOCH.sub.3                                                            H    7-C.sub.6 H.sub.4 -p-SO.sub.3 K                                                         6-CH.sub.2 CH.sub.2 NHCOOCH.sub.3                                                            H    CH.sub.2 COOCH.sub.3         6  4-CH.sub.2 NHCONHCH.sub.3                                                                    H    7-CH.sub.2 CH.sub.2 OH                                                                  6-CH.sub.2 NHCONHCH.sub.3                                                                    H    CH.sub.2 SO.sub.2                                                              N(CH.sub.3).sub.2            6  4-CH.sub.2 CONH.sub.2                                                                        H    7-CH.sub.2 Cl                                                                           6-CH.sub.2 CONH.sub.2                                                                        H    C.sub.6 H.sub.4p-NHCOOCH                                                       .sub.3                       6  5-CH.sub.2 CONHCH.sub.3                                                                      C.sub.4 H.sub.9n                                                                    7-C.sub.6 H.sub.4 -p-Br                                                                 6-CONH.sub.2  C.sub.2 H.sub.5                                                                     CH.sub.2 CH.sub.2                                                              CONH.sub.2                   6  4-CH.sub.2 CON(CH.sub.3).sub.2                                                               H    H        6-SO.sub.2 NH.sub.2                                                                          C.sub.2 H.sub.5                                                                     C.sub.6 H.sub.4                                                                -p-CONHCH.sub.3              6  4-CH.sub.2 CH.sub.2 OCH.sub.2 CH.sub.2 OC.sub.2 H.sub.5                                      H    4-COCH.sub.3                                                                            6-SO.sub.2 NHCH.sub.3                                                                        CH.sub.3                                                                            C.sub.6 H.sub.4                                                                -p-SCH.sub.3                 6  4-CH.sub.2 SC.sub.2 H.sub.5                                                                  H    4-NO.sub.2                                                                              6-SO.sub.2 N(C.sub.2 H.sub.5).sub.2                                                          C.sub.3 H.sub.7n                                                                    CH.sub.2 CH.sub.2                                                              SCH.sub.3                    6  5-CH.sub.2 SC.sub.6 H.sub.5                                                                  H    4-Cl     6-SO.sub.3 C.sub.6 H.sub.5                                                                   H    CH.sub.2C.sub.6 H.sub.4                                                        -p-SCH.sub.3                 6,7                                                                               4-CH.sub.2 SO.sub.2 C.sub.2 H.sub.5                                                          CH.sub.3                                                                            4-CN     6-SCH.sub.3   CH.sub.3                                                                            CH.sub.2 SO.sub.2                                                              C.sub.2 H.sub.5              6  2,4-di-CH.sub.2 SO.sub.2 C.sub.6 H.sub.5                                                     CH.sub.3                                                                            4-NHSO.sub.2 CH.sub.3                                                                   6,8-di-SCN    H    CH.sub.2 SO.sub.2 Ph         6  4-C.sub.6 H.sub.3 -o, -p-di-CN                                                               CH.sub.3                                                                            7-CH.sub.3                                                                              6-SO.sub.2 C.sub.6 H.sub.5                                                                   H    CH.sub.2 CH.sub.2                                                              OSO.sub.3 K                  6  4-C.sub.6 H.sub.2 -o, .sub.--m, - p-tri-Cl                                                   CH.sub.3                                                                            7-OCH.sub.3                                                                             6-CHO8-CN     H    C.sub.6 H.sub.4                                                                -p-OSO.sub.3 K               6  2,6-di-OSO.sub.3 Na                                                                          CH.sub.3                                                                            4-Ph     6-CONHC.sub.2 H.sub.5                                                                        H    CH.sub.2(C.sub.8                                                               H.sub.4 O.sub.2 N)           6  H             H    7-CH.sub.2 (C.sub.4 H.sub.4 O.sub.2 N)                                                  6-CON(C.sub.2 H.sub.5).sub.2                                                                 H    C.sub.2 H.sub.5              6  H             H    7-CH.sub.2 (C.sub.4 H.sub.3 O)                                                          6-C.sub.6 H.sub.11                                                                           H    C.sub.2 H.sub.5              6  5-CH.sub.2 (C.sub.8 H.sub.4 O.sub.2 N)                                                       H    H        6-SC.sub.6 H.sub.5                                                                           H    C.sub.2 H.sub.5              6  5-CH.sub.2 (C.sub.4 H.sub.3 O)                                                               H    H        6-NHSO.sub.2 C.sub.6 H.sub.5                                                                 H    C.sub.2 H.sub.5              __________________________________________________________________________

The invention has been described in detail with particular reference to preferred embodiments thereof, but it will be understood that variations and modifications can be effected within the spirit and scope of the invention. 

I claim:
 1. A dye having the structure: ##STR12## wherein R is a divalent radical of the formula ##STR13## which may be substituted in any position not occupied by a cinnamoyl group with an R₁ group comprising alkyl, alkenyl of 2-6 carbon atoms, aryl, cyclohexyl, alkoxy, halogen, hydroxy, alkylsulfonyl, cyano, carbamoyl, alkanoyl, alkanoyloxy, aroyl, alkoxycarbonyl, sulfamoyl, alkylsulfamoyl, dialkylsulfamoyl, alkanoylamino, SO₃ C₆ H₅, alkylthio, thiocyano, arylsulfonyl, formyl, alkylcarbamoyl, dialkylcarbamoyl, NO₂, --SO₃ M, --OSO₃ M, --COOH, aryloxy, arylthio, alkylsulfonylamino, aroylamino, arylsulfonylamino, and cyclohexylthio, wherein each of the alkyl, alkenyl, aryl, and cyclohexyl moieties of the above groups, is unsubstituted or substituted with 1-3 substituents different from the said moiety and independently selected from alkanoyloxy, alkyl, alkenyl, succinimido, --NO₂, alkanoylamino, alkylsulfonylamino, 1-(2-pyrrolidono), halogen, cyano, alkoxy, aryl, cyclohexyl, hydroxy, --SO₃ M, --OSO₃ M, aryloxy, furyl, aroyloxy, alkoxycarbonyl, --SO₂ N--(alkyl)₂, --NHCOO--alkyl, --NHCONH--alkyl, glutarimido, phthalimido, CONH₂, CONH--alkyl, CON(alkyl)₂, alkoxyalkoxy, alkylthio, arylthio, alkylsulfonyl, and arylsulfonyl, wherein M is selected from H⁺, NH₄ ⁺, Na⁺, K⁺, and the colorless cations of sulfuric acid or sulfonic acid salts of trimethylamine, triethylamine, tri(2-hydroxyethyl)amine, di(2-hydroxyethyl)amine, and N,N-dimethylaniline; and the coupler C¹ is selected from ##STR14## wherein R₁ is as defined above; R₂ and R₇ are each selected independently from hydrogen, alkyl, alkenyl of 2-6 carbons, aryl, and cyclohexyl, all of which groups are unsubstituted or substituted as defined above for the substituted R₁ groups; R₃, R₄ and R₈ are each selected from hydrogen and alkyl; and R₅ is H or alkyl.
 2. A dye of claim 1 wherein the coupler C¹ is ##STR15## wherein R₁, R₂, and R⁷ are as defined therein.
 3. A dye of claim 1 wherein the coupler C¹ is ##STR16## wherein R₁, R₃, R₄, R₇, and R₈ are as defined therein.
 4. A dye of claim 1 wherein the coupler C¹ is ##STR17## wherein R₁, R₃, and R₇ are as defined therein.
 5. A dye according to claim 1 wherein the benzothiazole or benzisothiazole ring is unsubstituted or substituted with 1-3 substituents independently selected from methoxycarbonyl, β-hydroxyethylcarbamoyl, β-potassiosulfatoethylcarbamoyl, methylcarbamoyl, carbamoyl, ethoxycarbonyl, and methyl; the cinnamoyl ring is unsubstituted or substituted with 1-3 substituents independently selected from alkyl, aralkyl, aralkyl substituted with --SO₃ M or --SO₄ M, cyclohexylalkyl, cyclohexylalkyl substituted with --SO₃ M or --SO₄, alkoxy, and alkanoylamino; R₂ is H, alkyl, aralkyl, aralkyl substituted with --SO₃ M or --SO₄ M, cyclohexylalkyl, cyclohexylalkyl substituted with --SO₃ M or --SO₄ M; R₇ is H, alkyl, aralkyl, aralkyl substituted with --SO₃ M or --SO₄ M, cyclohexylalkyl, cyclohexylalkyl substituted with --SO₃ M or --SO₄ M, sodio- or potassiosulfatoalkyl, sodio- or potassiosulfonicalkyl, or alkanoyloxyalkyl; the couplers are unsubstituted or substituted with 1-3 substituents independently selected from --SO₃ M halogen, --SO₄ M, alkyl, aralkyl, aralkyl substituted with --SO₃ M or --SO₄ M, alkanoylamino, aroylamino, cyclohexylalkyl, cyclohexylalkyl substituted with --SO₃ M or --SO₄ M, alkoxy, --COOH, and --OH; R₃, R₄ and R₈ are H or alkyl; and R₅ is hydrogen.
 6. A dye according to claim 1 wherein: the cinnamoyl ring is unsubstituted or substituted with halogen, COOH, OH, or SO₃ M; rings A and B are unsubstituted or substituted with methoxycarbonyl, β-hydroxyethylcarbamoyl, β-potassiosulfatoethylcarbamoyl, methylcarbamoyl, carbamoyl, ethoxycarbonyl, or methyl; and wherein, in an aniline coupler each substituent R₁ is a methyl, methoxy or acetamido group or a chlorine atom, each R₂ is hydrogen, a methyl or ethyl group, or a sulfonated cyclohexyl or benzyl group and each R₇ an ethyl or sulfonated ethyl group or an alkyl group of up to 4 carbon atoms substituted with a sulfonated phenyl group, each sulfonate group being of formula --SO₃ M, and wherein in a tetrahydroquinoline coupler R¹ and R³ are methyl groups, each of R₄ and R₈ is hydrogen or a methyl group, and R₇ is an ethyl group or a group of formula CH₂ CH₂ OCOCH₃ or CH₂ CH₂ OSO₃ M.
 7. The dye according to claim 1 having the formula ##STR18##
 8. The dye according to claim 1 having the formula ##STR19## 